PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Diethylene glycol hexyl ether; (n-Hexyl carbitol) | 112-59-4 |
14.01
4.01
11.01
14.02
4.08
4.05
7.01
8.00
11.00
4.09
|
||||||||||
| Formula | Synonyms | |||||||||||
| C10.H22.03 | DIETHYLENE GLYCOL N-HEXYL ETHER, HEXYL CARBITOL | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 190.32 | L | -33.3 | 259.1 | 0.01 | 20 | 0.935 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 7.2 | 79 | 480 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.92 | 10 | 62 |
Technical Basis
A review of available sources identified acute toxicity data (LD50, LDLo) for various species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route data, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2400 mg/kg)
This review generated a PAC-3 value consistent with Rev. 29A, and PAC-2 and PAC-1 values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 basis remain consistent, a rat oral LD50. The Rev. 29A TEEL-2 basis was a rabbit dermal TDLo that was not found in the current review and was instead derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodology remain consistent, with the difference in values due to the change of the TEEL-2.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2400 mg/kg)
This review generated a PAC-3 value consistent with Rev. 29A, and PAC-2 and PAC-1 values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 basis remain consistent, a rat oral LD50. The Rev. 29A TEEL-2 basis was a rabbit dermal TDLo that was not found in the current review and was instead derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodology remain consistent, with the difference in values due to the change of the TEEL-2.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Diethylene-glycol-monohexyl-ether.
Rat oral LD50: https://pubchem.ncbi.nlm.nih.gov/compound/Diethylene-glycol-monohexyl-ether.