PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dihydro-2H-pyran, 3,4- | 110-87-2 |
11.01
15.01
15.02
|
||||||||||
| Formula | Synonyms | |||||||||||
| O.(C.H2)3.C.H.C.H | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 84.13 | L mobile | 0.922 @ 19°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 14 | 150 | 910 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 4.1 | 44 | 260 |
Technical Basis
A review of limited sources identified rat oral LD50 toxicity data that was selected as the TEEL-3 basis and evaluated using factors in Tables 3.2, 3.3, and 3.4. TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (4600 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 was based on an HHR=2, while the current TEEL-3 is based on rat oral LD50 toxicity data. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-3 basis.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (4600 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 was based on an HHR=2, while the current TEEL-3 is based on rat oral LD50 toxicity data. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-3 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/3_4-dihydro-2H-pyran.
Rat oral LD50: https://chem.echa.europa.eu/100.003.465/dossier-view/0d16bb34-da65-4866-abbb-d8bb80864aa4/IUC5-54af7937-a5db-4f2f-a219-e0b88930aea1_16b5dabe-b30f-443d-b262-50584f49645e?searchText=110-87-2