Technical Basis
A review of available sources identified oral LD50 toxicity data for rat and mouse. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The oral LD50 of the most preferred species, rat, was selected as the TEEL-3 basis. TEEL-1 and -2 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (890 mg/kg)
This review generated TEEL values that are consistent with Rev. 29A*.