PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dimethyl phosphorochloridothioate | 2524-03-0 | 2267 |
14.01
11.01
14.02
8.00
4.10
4.07
3.05
7.11
10.00
3.06
|
|||||||||
| Formula | Synonyms | |||||||||||
| C2.H6.Cl.O2.P.S | DIMETHYL CHLOROTHIOPHOSPHATE, CHLORODIMETHOXYPHOSPHINE SULFIDE, CHLOROTHIOPHOSPHATE DE DIMÉTHYLE (DOT FRENCH), CLOROTIOFOSFATO DE DIMETILO (DOT SPANISH), CLORURO DE DIMETIL TIOFOSFORILO (DOT SPANISH), DIMETHOXY THIOPHOSPHONYL CHLORIDE, DIMETHYL CHLOROPHOSPHOROTHIOATE, DIMETHYL CHLOROTHIONOPHOSPHATE, DIMETHYL PHOSPHOROCHLORIDOTHIOATE, DIMETHYL THIONOPHOSPHOROCHLORIDATE, DIMETHYL THIOPHOSPHOROCHLORIDATE, METHYL PCT, METHYL PHOSPHOROCHLORIDOTHIOATE ((MEO)2CLPS), O,O-DIMETHYL CHLOROPHOSPHOROTHIOATE, O,O-DIMETHYL CHLOROTHIONOPHOSPHATE, O,O-DIMETHYL CHLOROTHIOPHOSPHATE, O,O-DIMETHYL PHOSPHOROCHLORIDOTHIOATE, O,O-DIMETHYL PHOSPHOROCHLOROTHIOATE, O,O-DIMETHYL PHOSPHOROTHIONOCHLORIDATE, O,O-DIMETHYL THIONOPHOSPHOROCHLORIDATE, O,O-DIMETHYL THIOPHOSPHORIC ACID CHLORIDE, O,O-DIMETHYL THIOPHOSPHORYL CHLORIDE, O,O-DIMETHYLPHOSPHOROCHLORIDOTHIOATE, O,O-DIMETHYLTHIONOPHOSPHORYL CHLORIDE, PHOSPHONOTHIOIC ACID, CHLORO-, O,O-DIMETHYL ESTER, PHOSPHOROCHLORIDITHIOATE DE DIMÉTHYLE (DOT FRENCH), PHOSPHOROCHLORIDOTHIOIC ACID, O,O-DIMETHYL ESTER | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 160.56 | L | 4 | 40 | 1.326 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.29 | 3.2 | 15 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.044 | 0.49 | 2.3 |
Technical Basis
A review of available sources identified rat and mouse acute toxicity data (LC50, LD50) for inhalation and oral exposures, and a Level of Concern (LOC). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The data of the most preferred species and exposure, a rat LC50, was selected as the TEEL-3 basis and was scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). The LOC was selected as the TEEL-2. The TEEL-1 value was derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC (0.0032 g/m3)
• TEEL-3 = Rat LC50 (340 mg/m3/4H)
This review generated TEEL values that are consistent with Rev. 29A*.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC (0.0032 g/m3)
• TEEL-3 = Rat LC50 (340 mg/m3/4H)
This review generated TEEL values that are consistent with Rev. 29A*.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Dimethyl-chlorothiophosphate
LOC: Retrieved from Appendix C (page C-4): https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
Rat LC50: Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, -(56), 1982. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Dimethyl-chlorothiophosphate