PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dimethyl-5-phenylphenazinium chloride, 3,7-diamino-2,8-; (Safranine; Gossypimine) | 477-73-6 |
7.01
11.00
4.01
14.01
|
||||||||||
| Formula | Synonyms | |||||||||||
| C20.H19.N4.Cl | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 350.88 | S |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.17 | 1.9 | 11 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.012 | 0.13 | 0.77 |
Technical Basis
A review of available sources identified the mouse and rat acute toxicity data (LD50, LDLo) acute for intravenous and oral routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were subsequently down selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species data, a rat intravenous LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat intravenous LD50 (28740 µg/kg)
This review generated TEEL values consistent with Rev. 29A.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat intravenous LD50 (28740 µg/kg)
This review generated TEEL values consistent with Rev. 29A.
References
Stanford Medical Bulletin., 9(96), 1951 [PMID:14855182]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Basic-red-2
https://www.sigmaaldrich.com/US/en/substance/safranino35084477736