PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dimethylbenzidene 3,3'-; (o-Tolidine) | 119-93-7 |
13.00
15.01
11.01
4.09
4.04
4.10
4.03
2.00
3.09
3.10
|
||||||||||
| Formula | Synonyms | |||||||||||
| C14H16N2 | 3,3^-DIMETHYLBENZIDINE, (1,1'-BIPHENYL)-4,4'-DIAMINE-3,3'-DIMETHYL-, 2-TOLIDINE, 3,3'-DIMETHYL-(1,1'-BIPHENYL)-4,4'-DIAMINE, 3,3'-DIMETHYL-4,4'-BIPHENYLDIAMINE, 3,3'-DIMETHYL-4,4'-DIAMINOBIPHENYL, 3,3'-DIMETHYL-4,4'-DIPHENYLDIAMINE, 3,3'-DIMETHYLBENZIDIN, 3,3'-DIMETHYLBIPHENYL-4,4'-DIAMINE, 3,3'-DIMETHYLDIPHENYL-4,4'-DIAMINE, 3,3'-TOLIDINE, 4,4'-BI-O-TOLUIDINE, 4,4'-DI-O-TOLUIDINE, 4,4'-DIAMINO-3,3'-DIMETHYLBIPHENYL, 4,4'-DIAMINO-3,3'-DIMETHYLDIPHENYL, BENZIDINE, 3,3'-DIMETHYL-, BIANISIDINE, C.I. 37230, C.I. AZOIC DIAZO COMPONENT 113, C.I. 37230, C.I. AZOIC DIAZO COMPONENT 113, DIAMINODITOLYL, FAST DARK BLUE BASE R, O,O'-TOLIDINE, O-TOLIDIN, O-TOLIDINE, RCRA WASTE NUMBER U095, TOLIDINE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 212.29 | S | 131 | 300 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.0018 | 0.020 | 36 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.00021 | 0.0023 | 4.1 |
Technical Basis
A review of available sources identified the following: dog and mouse LDLo acute toxicity data for intraperitoneal and oral routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Although dog is the most preferred species, the mouse data was selected as the TEEL-3 basis because it was 1) the most current (1954 vs. 1907), and 2) resulted in a more conservative TEEL-3. The REL-C was selected as the TEEL-2. The TEEL-1 value was derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = REL-C (0.02 mg/m3)
• TEEL-3 = Mouse intraperitoneal LDLo (125 mg//kg)
This review generated TEEL values that are consistent with Rev. 29A*.
• TEEL-1 = TEEL-2/11
• TEEL-2 = REL-C (0.02 mg/m3)
• TEEL-3 = Mouse intraperitoneal LDLo (125 mg//kg)
This review generated TEEL values that are consistent with Rev. 29A*.
References
REL-C: https://www.osha.gov/chemicaldata/151
Mouse intraperitoneal LDLo. Summary Tables of Biological Tests, National Research Council Chemical-Biological Coordination Center., 6(64), 1954. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/3_3_-Dimethylbenzidine.
Dog oral LDLo (600 mg/kg). Archiv fuer Experimentelle Pathologie und Pharmakologie., 58(167), 1907. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/3_3_-Dimethylbenzidine.