PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Dinoseb; (2-sec-Butyl-4,6-dinitrophenol) 88-85-7 2779
17.00
14.01
4.01
11.01
4.08
4.05
7.01
8.00
11.00
4.09
Formula Synonyms
C10H12N2O5 DINOSEB, 2,4-DINITRO-6-(1-METHYLPROPYL)PHENOL, 2,4-DINITRO-6-SEC- BUTYLPHENOL, 2,4-DINITRO-6-SEC-BUTYLPHENOL, 2-(1-METHYLPROPYL)-4,6-DINITROPHENOL, 2-SEC-BUTYL-4,6-DINITROPHENOL, 4,6-DINITRO-2- SEC-BUTYLPHENOL, 4,6-DINITRO-2-(1-METHYL-N-PROPYL)PHENOL, 4,6-DINITRO-2-(2-BUTYL)PHENOL, 4,6-DINITRO-2-SEC-BUTYLPHENOL, 4,6-DINITRO-O-SEC-BUTYLPHENOL, 6-SEC-BUTYL-2,4-DINITROPHENOL, AATOX, ARETIT, BASANITE, BLAARTOX, BNP 20, BNP 30, BUTAPHEN, BUTAPHENE, CALDON, CHEMOX GENERAL, CHEMOX P.E., CHEMOX PE, DBNF, DESICOIL, DIBUTOX, DIBUTOX 20CE, DINITRALL, DINITRO WEED KILLER, DINITRO-ORTHO-SEC-BUTYL PHENOL, DINITROBUTYL PHENOL, DINITROBUTYLPHENOL, DN 289, DNBP, DNOSBP, DNSBP, DOW GENERAL, DOW GENERAL WEED KILLER, DOW SELECTIVE WEED KILLER, DYTOP, ELGETOL, ELGETOL 318, ENT 1,122, GEBUTOX, HIVERTOX, KILOSEB, KNOXWEED, LADOB, LASEB, LIRO DNBP, NITROPONE, PHENOL, 2-(1-METHYLPROPYL)-4,6-DINITRO-, PHENOL, 2-(L-METHYLPROPYL)-4,6-DINITRO-, PHENOL, 2-SEC-BUTYL-4,6- DINITRO-, PHENOL, 2-SEC-BUTYL-4,6-DINITRO-, PHENOTAN, PNOSBP, PREMERG, PREMERGE, PREMERGE 3, SINOX GENERAL, SPARIC, SPURGE, SUBITEX, UNICORP DNBP, VERTAC DINITRO WEED KILLER, WSX 8365
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
240.21 S 40 1 151.1 1.265 @ 45°C
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.41 4.5 4.8
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.042 0.46 0.49
Technical Basis
A review of available sources identified the following: a Level of Concern (LOC) exposure limit and LD50 (guinea pig, rat) acute toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected based on the type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2. These were evaluated using factors in Tables 3.2, 3.3, and 3.4. The lowest dose for the most preferred species and route, a rat LD50 (24 mg/kg) was selected as the TEEL-3 basis. The LOC exposure limit was selected for TEEL-2. TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC
• TEEL-3 = Rat Oral LD50 (24 mg/kg)
This review generated TEEL-2 and TEEL-1 values consistent with Rev. 29A. The Rev. 29A TEEL-3 and current basis are both rat oral LD50¬; however, the current source is the most current and lowest dose available (Section 3.3.1).
References
Appendix C, pg. C-4. https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
Rat oral LD¬50, 1984, (24 mg/kg). Retrieved from: https://echa.europa.eu/sk/registration-dossier/-/registered-dossier/12446/7/3/1
Rat oral LD50, 1965 (25 mg/kg). Toxicology and Applied Pharmacology, 7,353,1965. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Dinoseb.
Rat oral LD50, 1989 (27 mg/kg). Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 519. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/source/hsdb/1445
Search Again
PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.