PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dioctyl sebacate; (Bis(2-ethylhexyl) sebacate) | 122-62-3 |
19.00
|
||||||||||
| Formula | Synonyms | |||||||||||
| C26.H50.O4 | BIS(2-ETHYLHEXYL) SEBACATE, 1-HEXANOL, 2-ETHYL-, SEBACATE, 2-ETHYLHEXYL SEBACATE, BIS(2-ETHYLHEXYL) DECANEDIOATE, BIS(ETHYLHEXYL) SEBACATE, BISOFLEX, BISOFLEX DOS, DECANEDIOIC ACID DI(2-ETHYLHEXYL) ESTER, DECANEDIOIC ACID, BIS(2-ETHYLHEXYL) ESTER, DEHS, DI(2-ETHYLHEXYL) SEBACATE, DI-2-ETHYLHEXYL SEBACATE, DIOCTYL SEBACATE, DOS, EDENOL 888, EDENOR DEHS, ERGOPLAST SDO, ERGOPLAST SNO, MONOPLEX DOS, OCTOIL S, OCTYL SEBACATE, PLASTHALL DOS, PLEXOL, PLEXOL 201, PLEXOL 201J, PX 438, REOLUBE DOS, REOMOL DDS, SANSOCIZER DOS, SEBACIC ACID DI(2-ETHYLHEXYL) ESTER, SEBACIC ACID DI-2-ETHYLHEXYL DIESTER, SEBACIC ACID, BIS(2-ETHYLHEXYL) ESTER, STAFLEX DOS | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 426.76 | L | -48 | 0.914 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 30 | 560 | 3400 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.7 | 32 | 190 |
Technical Basis
A review of available sources identified an exposure limit (OEL-TWA) and acute toxicity data (LD50) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route data, a rat oral LD50, was selected as the TEEL-3 basis. The TEEL-2 was derived according to Table 3.5. The OEL-TWA (Latvia) was selected as the TEEL-1 basis.
• PAC-1 = TEEL-1 = OEL-TWA (10 mg/m3, Latvia) x 3
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (17000 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was rat intravenous (LD50) from which the TEEL-2 and TEEL-1 were derived (Table 3.5). Instead, the current review selected a rat oral LD50 as the TEEL-3 basis, derived TEEL-2 from the TEEL-3 (Table 3.5), and selected an OEL-TWA (Latvia) as the TEEL-1 basis.
• PAC-1 = TEEL-1 = OEL-TWA (10 mg/m3, Latvia) x 3
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (17000 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was rat intravenous (LD50) from which the TEEL-2 and TEEL-1 were derived (Table 3.5). Instead, the current review selected a rat oral LD50 as the TEEL-3 basis, derived TEEL-2 from the TEEL-3 (Table 3.5), and selected an OEL-TWA (Latvia) as the TEEL-1 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Bis_2-ethylhexyl_-sebacate.
OEL-TWA: https://ilv.ifa.dguv.de/limitvalues/23706
Rat LD50: BIBRA (1996). Toxicity Profile for Di(2-ethylhexyl) Sebacate. 6 pp. British Industrial Biological Research Association (BIBRA) and references therein cited. Retrieved from (see Hazard Data > Hazard > Mortality Response Summary Value): https://comptox.epa.gov/dashboard/chemical/details/DTXSID7025055