PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dipropylamine | 142-84-7 | 2383 |
14.02
14.01
4.01
11.01
7.01
11.00
4.07
3.02
4.11
|
|||||||||
| Formula | Synonyms | |||||||||||
| C6H15N | DIPROPYLAMINE, DI-N-PROPYLAMINE, DIPROPANAMINE, DIPROPILAMINA (DOT SPANISH), DIPROPYLAMINE (DOT FRENCH), N-DIPROPYLAMINE, N-PROPYL-1-PROPANAMINE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 101.19 | L | -63 | 109.3 | 7.5 | 6 | 0.7400 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 2.9 | 32 | 190 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.70 | 7.7 | 46 |
Technical Basis
A review of available sources identified the following: LC50 (rat and mouse) and LD50 (various species) toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluating using factors in Tables 3.2, 3.3, and 3.4. Inhalation exposures were scaled to 60-minute equivalents using the ten Berge equation (Section 3.3.4.). The most preferred species and route, the rat LC50, was selected as the TEEL-3 basis. TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (4400 mg/m3/4H)
This review generated TEEL values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis is a rat oral LD50¬, while the current basis is an LC50, a more preferred route (LC50 > LD50, Table 3.1). The TEEL-2 and TEEL-1 methodology used in Rev. 29A and the current review are consistent, with differences due to the change in TEEL-3.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (4400 mg/m3/4H)
This review generated TEEL values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis is a rat oral LD50¬, while the current basis is an LC50, a more preferred route (LC50 > LD50, Table 3.1). The TEEL-2 and TEEL-1 methodology used in Rev. 29A and the current review are consistent, with differences due to the change in TEEL-3.
References
https://cameochemicals.noaa.gov/chris/DNA.pdf
Rat LC50:Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, (63), 1982 via PubChem; National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 8902, Dipropylamine. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Dipropylamine.