PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Di-tert-butyl dicarbonate 24424-99-5
11.00
11.01
15.01
15.02
Formula Synonyms
C10.H18.O5
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
218.28 L
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.067 0.73 4.4
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.0075 0.082 0.49
Technical Basis
A review of available sources identified rat acute toxicity data (LC50, LD50). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred route toxicity data, rat LC50, was selected as the TEEL-3 basis and scaled to 60-minute equivalent using the ten Berge equation (Section 3.3.4). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (100 mg/m3/4H)
This review generated TEEL values that are consistent with Rev. 29A*.
References
Rat LC50; National Technical Information Service., OTS0538278. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Di-tert-butyl-dicarbonate
Rat LD50 oral (>5,000 mg/kg). Retrieved from: https://echa.europa.eu/registration-dossier/-/registered-dossier/5501/7/3/2
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.