PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dodecane | 112-40-3 |
17.00
15.01
11.01
15.02
4.08
7.01
11.00
4.02
7.11
7.10
|
||||||||||
| Formula | Synonyms | |||||||||||
| C12H26 | N-DODECANE, ADAKANE 12, BA 51-090453, BIHEXYL, C12-N-ALKANE, DIHEXYL, DODECANE, DUODECANE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 170.38 | L | -9.6 | 216.3 | 0.135 | 25 | 0.749 @ 20°C | 6000 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.12 | 1.3 | 7.9 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.84 | 9.1 | 55 |
Technical Basis
A review of available data sources identified the following: rat LC50 and mouse intravenous LDLo toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Collected toxicity data were evaluated for their relative preference and the rat LC50 ¬toxicity data selected as the TEEL-3 basis. The LC50 was scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (142 ppm/8H)
This review generated TEEL values more conservative than those in Rev. 29A. The Rev. 29A TEEL-3 basis was a mouse oral LDLo, while the current basis is more preferred species, route, and exposure type (rat > mouse, inhalation > intravenous, LC50 > LDLo). The Rev. 29A and current were both derived according to Table 3.5 and are inconsistent due to the change in TEEL-3 basis.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (142 ppm/8H)
This review generated TEEL values more conservative than those in Rev. 29A. The Rev. 29A TEEL-3 basis was a mouse oral LDLo, while the current basis is more preferred species, route, and exposure type (rat > mouse, inhalation > intravenous, LC50 > LDLo). The Rev. 29A and current were both derived according to Table 3.5 and are inconsistent due to the change in TEEL-3 basis.
References
Pharmacology and Toxicology, 62(259), 1988 [PMID:3413027]. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Dodecane