PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dodecylphenol, 4- (mixture of isomers) | 27193-86-8 |
13.00
15.01
11.01
14.02
4.08
11.00
4.09
4.06
4.07
3.10
|
||||||||||
| Formula | Synonyms | |||||||||||
| C18.H30.O | DODECYL PHENOL | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 262.48 | L/S | 175 | 0.93 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 6.3 | 69 | 420 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.59 | 6.4 | 39 |
Technical Basis
A review of available sources identified acute toxicity data (LD50) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route toxicity data, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2100 mg/kg)
This review generated a PAC-3 value consistent with Rev. 29A and inconsistent PAC-2 and PAC-1 values. The Rev. 29A and current TEEL-3 source, and methodologies are consistent. The Rev. 29A TEEL-2 basis was a rat TDLo that was not found during the review; instead, the current TEEL-2 was derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodologies are consistent, with differences due to the change in TEEL-2.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2100 mg/kg)
This review generated a PAC-3 value consistent with Rev. 29A and inconsistent PAC-2 and PAC-1 values. The Rev. 29A and current TEEL-3 source, and methodologies are consistent. The Rev. 29A TEEL-2 basis was a rat TDLo that was not found during the review; instead, the current TEEL-2 was derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodologies are consistent, with differences due to the change in TEEL-2.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/171144
Rat LD50. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 72, 1990. Retrieved from: https://comptox.epa.gov/dashboard/chemical/hazard/DTXSID1027926 (Hazard Data > Hazard > Mortality Response Summary Value)