Technical Basis
A review of available sources identified acute toxicity data (LD50) for various species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route data, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2386 mg/kg)
This review generated PAC values that are consistent with Rev. 29A*.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Dysprosium-nitrate.
Chemical phase information: https://m.chemicalbook.com/ChemicalProductProperty_EN_CB2931607.htm
Rat oral LD50: Environmental Quality and Safety, Supplement., 1(1), 1975 [PMID:1057514]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Dysprosium-nitrate.