PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ethyl S,S-dipropylphosphorodithioate, O-; (Mocap PC-84; Ethoprophos) | 13194-48-4 | 3018 |
6.00
14.01
4.01
11.01
4.08
4.05
7.01
8.00
7.00
11.00
|
|||||||||
| Formula | Synonyms | |||||||||||
| C8H19O2PS2 | ETHOPROPHOS, ENT 27,318, ENT 27318, ETHOPROP, ETHYL PROPYL PHOSPHORODITHIOATE ((ETO)(PRS)2PO), JOLT, MOCAP, MOCAP 10G, MOCAP 6EC, O-ETHYL S,S-DIPROPYL DITHIOPHOSPHATE, O-ETHYL S,S-DIPROPYL PHOSPHORODITHIOATE, O-ETHYL S,S-DIPROPYLPHOSPHORODITHIOATE, PHOSPHORODITHIOIC ACID O-ETHYL S,S-DIPROPYL ESTER, PHOSPHORODITHIOIC ACID, O-ETHYL S,S-DIPROPYL ESTER, PROFOS, PROPHOS, PROPHOS (ESTER), ROVOKIL, S,S-DIPROPYL O-ETHYL PHOSPHORODITHIOATE, V-C CHEMICAL V-C 9-104, VC 9-104, VC9-104 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 242.34 | L | -13 | 0.00038 | 25 | 1.09 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.082 | 0.90 | 5.4 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.0083 | 0.091 | 0.54 |
Technical Basis
A review of available sources identified acute toxicity data (LC50, LD50) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. A rat LD50 and LC50 were evaluated as TEEL bases. No duration was reported for the rat LC50; therefore, a duration of 4-hours was assumed (Section 3.3.2) and it was scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). The rat LD50 and LC50 resulted in comparable TEEL-3 values (6.5 and 5.4, respectively); considering each source and the lowest resultant TEEL (Section 3.3.1), the rat LC50 (EPA) was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (0.123 mg/L/(4H assumed))
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat oral LD50, while the current basis is a rat LC50 a more preferred route with an assumed 4-hour duration (inhalation > oral, Section 3.3.2). The Rev. 29A and current TEEL-2/TEEL-1 were derived using the same methodology (Table 3.5), with differences due to the change in TEEL-3.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (0.123 mg/L/(4H assumed))
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat oral LD50, while the current basis is a rat LC50 a more preferred route with an assumed 4-hour duration (inhalation > oral, Section 3.3.2). The Rev. 29A and current TEEL-2/TEEL-1 were derived using the same methodology (Table 3.5), with differences due to the change in TEEL-3.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Ethoprophos.
Rat LC50 (0.123 mg/L). See Table 1, pg. 7 retrieved from: https://www3.epa.gov/pesticides/chem_search/cleared_reviews/csr_PC-041101_2-Sep-99_042.pdf
Rat oral LD50 (33 mg/kg) Krieger, R. (ed.). Handbook of Pesticide Toxicology. Volume 1, 2nd ed. 2001. Academic Press, San Diego, California., p. 693. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/source/hsdb/1715