PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amitrole | 61-82-5 |
15.01
4.01
4.05
7.00
11.00
4.07
2.02
3.02
5.10
4.11
|
||||||||||
| Formula | Synonyms | |||||||||||
| C2H4N4 | AMITROLE, 1H-1,2,4-TRIAZOL-3-AMINE, 2,3,5,6-TETRAAZABICYCLO[2.1.1]HEX-1-ENE, 2-AMINO-1,3,4-TRIAZOLE, 2-AMINOTRIAZOLE, 3,A-T, 3-AMINO-1,2,4-TRIAZOLE, 3-AMINO-1H-1,2,4-TRIAZOLE, 3-AMINO-S-TRIAZOLE, 3-AMINOTRIAZOLE, 5-AMINO-1,2,4-TRIAZOLE, 5-AMINO-1H-1,2,4-TRIAZOLE, AMEROL, AMINO TRIAZOLE WEEDKILLER 90, AMINOTRIAZOL-SPRITZPULVER, AMINOTRIAZOLE, AMINOTRIAZOLE (PLANT REGULATOR), AMITOL, AMITRIL, AMITRIL T.L., AMITROL, AMITROL 90, AMITROL-T, AMIZOL, AMIZOL D, AMIZOL DP NAU, AMIZOL F, AT, AT LIQUID, AT-90, ATA, ATA (AMINE), AZAPLANT, AZAPLANT KOMBI, AZOLAN, AZOLE, CAMPAPRIM A 1544, CYTROL, CYTROL AMITROLE-T, CYTROLE, DIUROL, DIUROL 5030, DOMATOL, DOMATOL 88, ELMASIL, EMISOL, EMISOL 50, EMISOL F, ENT 25445, FENAMINE, FENAVAR, HERBIDAL TOTAL, HERBIZOLE, KLEER-LOT, ORGA-414, RADOXONE TL, RAMIZOL, RCRA WASTE NUMBER U011, S-TRIAZOLE, 3-AMINO-, SIMAZOL, SOLUTION CONCENTREE T271, TRIAZOLAMINE, USAF XR-22, VOROX, VOROX AA, VOROX AS, WEEDAR ADS, WEEDAR AT, WEEDAZIN, WEEDAZIN ARGINIT, WEEDAZOL, WEEDAZOL GP2, WEEDAZOL SUPER, WEEDAZOL T, WEEDAZOL TL, WEEDEX GRANULAT, WEEDOCLOR, X-ALL LIQUID | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 84.08 | S | 159 | 25 | 1.138 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.6 | 36 | 220 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.47 | 10 | 64 |
Technical Basis
A review of available sources identified exposure limits (STELs, TWAs) and acute toxicity data (LD50) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred route and species toxicity data, a rat oral LD50, was selected as the TEEL-3 basis. The TEEL-2 value was derived according to Table 3.5. The MAK-STEL (Germany, AGS/MAK; inhalable fraction, 15-minutes) was selected as the TEEL-1.
• TEEL-1 = MAK-STEL (inhalable fraction, 15-minutes, 1.6 mg/m3)
• TEEL-2 = TEEL-3/6
• TEEL-3 = LD50 rat oral (1100 mg/kg)
This review generated TEEL-2 and TEEL-1 values inconsistent with Rev. 29A. The Rev. 29A TEEL-2 was a rat TDLo not found during the review. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 is a short term occupational exposure limit (MAK-STEL). The Rev. 29A and current TEEL-3 values, source, and methodology are consistent.
• TEEL-1 = MAK-STEL (inhalable fraction, 15-minutes, 1.6 mg/m3)
• TEEL-2 = TEEL-3/6
• TEEL-3 = LD50 rat oral (1100 mg/kg)
This review generated TEEL-2 and TEEL-1 values inconsistent with Rev. 29A. The Rev. 29A TEEL-2 was a rat TDLo not found during the review. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 is a short term occupational exposure limit (MAK-STEL). The Rev. 29A and current TEEL-3 values, source, and methodology are consistent.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Amitrole
OEL STELs and TWAs: https://ilv.ifa.dguv.de/limitvalues/2480
LD50: Residue Reviews., 10(97), 1965 [PMID:4865270]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Amitrole