PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ethylenediaminetetraacetic acid; (EDTA) | 60-00-4 | 9117 |
15.01
11.01
15.02
4.05
4.09
4.06
4.04
4.10
4.07
3.09
|
|||||||||
| Formula | Synonyms | |||||||||||
| C10H16N2O8 | EDTA, (ETHYLENEDINITRILO) TETRAACETIC ACID, 3,6-DIAZAOCTANEDIOIC ACID, 3,6-BIS(CARBOXYMETHYL)-, ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, ACETIC ACID, 2,2^,2'',2'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS, ACIDE ÉTHYLÈNEDIAMINO-TÉTRAACÉTIQUE (DOT FRENCH), ACIDO ETILENDIAMINOTETRAACÉTICO (DOT SPANISH), CELON A, CELON ATH, CHEELOX, CHEMCOLOX 340, CLEWAT TAA, COMPLEXON II, EDATHAMIL, EDETIC ACID, EDTA (CHELATING AGENT), EDTA (DOT FRENCH), EDTA (DOT SPANISH), ENDRATE, ETHYLENE BIS (IMINODIACETIC ACID), ETHYLENEDIAMINE TETRACETIC ACID, ETHYLENEDIAMINE-N,N,N',N'-TETRAACETIC ACID, ETHYLENEDIAMINE-TETRAACETIC ACID (EDTA), ETHYLENEDIAMINETETRAACETIC ACID, ETHYLENEDINITRILOTETRAACETIC ACID, GLUMA CLEANSER, HAVIDOTE, ICRF 185, METAQUEST A, NERVANAID B ACID, NULLAPON B ACID, NULLAPON BF ACID, PERMA KLEER 50 ACID, SEQUESTRENE AA, SEQUESTRIC ACID, SEQUESTROL, TETRINE ACID, TITRIPLEX, TITRIPLEX II, TRILON BS, TRILON BW, VERSENE, VERSENE ACID, YD 30 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 292.24 | S |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 2.4 | 26 | 160 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.20 | 2.2 | 13 |
Technical Basis
A review of available sources identified acute toxicity data (LD50) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The lowest reported dose for the most preferred species and route, a rat intraperitoneal LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat intraperitoneal LD50 (397 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat intraperitoneal LD50; the current TEEL-3 basis is also a rat intraperitoneal, but for a lower reported dose. The Rev. 29A TEEL-2 basis was a rat TDLo not found during the current review, while the current TEEL-2 was derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 use the same methodology, with differences due to the change in TEEL-2.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat intraperitoneal LD50 (397 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat intraperitoneal LD50; the current TEEL-3 basis is also a rat intraperitoneal, but for a lower reported dose. The Rev. 29A TEEL-2 basis was a rat TDLo not found during the current review, while the current TEEL-2 was derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 use the same methodology, with differences due to the change in TEEL-2.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Edetic-Acid
Rat LD50. Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology., 13(295), 1962 [PMID:14035030]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Edetic-Acid