PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ethylenethiourea; (2-Imidazolidinethione) | 96-45-7 |
4.06
4.10
3.08
2.02
3.10
3.09
3.02
5.00
5.10
16.01
|
||||||||||
| Formula | Synonyms | |||||||||||
| C3H6N2S | ETHYLENE THIOUREA, 1,3-ETHYLENE-2-THIOUREA, 1,3-ETHYLENETHIOUREA, 2-IMIDAZOLIDINE-2-THIONE, 2-IMIDAZOLIDINETHIONE, 2-IMIDAZOLINE-2-THIOL, 2-MERCAPTO-2-IMIDAZOLINE, 2-MERCAPTO-4,5-DIHYDROIMIDAZOLE, 2-MERCAPTOIMIDAZOLINE, 2-THIOIMIDAZOLIDINE, 2-THIOL-DIHYDROGLYOXALINE, 4,5-DIHYDRO-2-MERCAPTOIMIDAZOLE, 4,5-DIHYDROIMIDAZOLE-2(3H)-THIONE, ACCEL 22, ACCEL 22S, END 75, ETC, ETHYLENETHIOCARBAMIDE, ETHYLENETHIOUREA, ETU, IMIDAZOLE-2(3H)-THIONE, 4,5-DIHYDRO-, IMIDAZOLIDINETHIONE, IMIDAZOLINE, 2-MERCAPTO-, IMIDAZOLINE-2(3H)-THIONE, IMIDAZOLINE-2-THIOL, IMIDIZOLIDENETHIONE, MERCAPTOIMIDAZOLINE, MERCAZIN I, N,N^-ETHYLENETHIOUREA, N,N-ETHYLENETHIOUREA, NA 22, NA-22, NA-22-D, NCI-C03372, NOCCELER 22, PENNAC CRA, RCRA WASTE NUMBER U116, RHENOGRAN ETU, RHODANIN S 62, RODANIN S 62, SANCELER 22, SANCELER 22C, SODIUM-22 NEOPRENE ACCELERATOR, SOXINOL 22, TETRAHYDRO-2H-IMIDAZOLE-2-THIONE, THIOUREA, N,N'-1,2-ETHANEDIYL-, UREA, 1,3-ETHYLENE-2-THIO-, USAF EL-62, VULKACIT NPV/C, VULKACIT NPV/C2, WARECURE C | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 102.16 | S | 203 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.60 | 18 | 110 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.14 | 4.3 | 26 |
Technical Basis
A review of available sources identified mouse and rat acute toxicity data (LD50) for oral routes and an OEL exposure limits (TWA, STEL). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The lowest dose rat oral LD50 was selected as the TEEL-3 basis. TEEL-2 values were derived according to Table 3.5. A 15-minute OEL-STEL (Finland) was selected as the TEEL-1.
• TEEL-1 = OEL-STEL (Finland, 15-minute)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (545 mg/kg)
This review generated TEEL-2 and TEEL-1 values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 values, source, and methodology are consistent. The Rev. 29A TEEL-2 basis was a rat oral TDLo not found during the review. Instead, the TEEL-2 values were derived from the TEEL-3. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 is a 15-minute occupational short-term exposure limit (OEL-STEL, Finland).
• TEEL-1 = OEL-STEL (Finland, 15-minute)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (545 mg/kg)
This review generated TEEL-2 and TEEL-1 values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 values, source, and methodology are consistent. The Rev. 29A TEEL-2 basis was a rat oral TDLo not found during the review. Instead, the TEEL-2 values were derived from the TEEL-3. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 is a 15-minute occupational short-term exposure limit (OEL-STEL, Finland).
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Ethylene-thiourea.
Rat oral LD50 (545 mg/kg). WHO; Environ Health Criteria 78: Dithiocarbamate Pesticides, Ethylenethiourea And Propylenethiourea: A General Introduction (1988). Retrieved from: https://pubchem.ncbi.nlm.nih.gov/source/hsdb/1643
OEL-STEL (Finland, 15-minute). https://ilv.ifa.dguv.de/limitvalues/27973