PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ferric chloride | 7705-08-0 | 1773 |
6.00
15.01
11.01
15.02
4.08
4.05
11.00
4.09
4.10
4.07
|
|||||||||
| Formula | Synonyms | |||||||||||
| Cl3Fe | FERRIC CHLORIDE, CHLORURE DE FER III (DOT FRENCH), CHLORURE DE FER III, ANHYDRE (DOT FRENCH), CLAYFEC, CLORURO FÉRRICO (DOT SPANISH), CLORURO FÉRRICO, ANHIDRO (DOT SPANISH), FE(NO3)3: FERRIC NITRATE, IRON(III) NITRATE, FE(SO4)3: FERRIC SULFATE, IRON(III) SULFATE, FECL2: FERROUS CHLORIDE, IRON(II) CHLORIDE, FECL3: FERRIC CHLORIDE, IRON(III) CHLORIDE, FERRIC CHLORIDE, ANHYDROUS, FERRIC CHLORIDE, HEXAHYDRATE, FERRIC CHLORIDE, SOLUTION, FERRIC CHLORIDE, SOLID (DOT), FERRIC CHLORIDE, SOLID, ANHYDROUS (DOT), FERRIC CHLORIDE, SOLUTION (DOT), FERRIC TRICHLORIDE, FESO4: FERROUS SULFATE, IRON(II) SULFATE, FLORES MARTIS, IRON (III) CHLORIDE, IRON CHLORIDE, IRON CHLORIDE, SOLID (DOT), IRON III CHLORIDE, IRON PERCHLORIDE, IRON SESQUICHLORIDE, SOLID (DOT), IRON TRICHLORIDE, IRON(III) CHLORIDE, TRIFLOC, UN 1773 (DOT), UN 2582 (DOT) | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 162.2 | S plates | 307.6 | 1 | 194 | 2.9 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 8.7 | 15 | 89 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.3 | 2.3 | 13 |
Technical Basis
A review of available sources identified the following: TLV-TWA for soluble iron (Fe, CASRN: 1309-37-1,) LDLo (human,) and LD50 (rat) for intraperitoneal and oral routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route based on the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Although human toxicity is highly preferred, the dose was reported in mL/kg and no additional information was available for the necessary unit conversion. Of two available rat oral LD50 toxicities identified, the most recent, verifiable dose was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = MW-adjusted TLV-TWA (soluble Fe)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (450 mg/kg)
This review generated TEEL-3 and TEEL-2 values that are more conservative than those in Rev. 29A, and a TEEL-1 which is consistent. In Rev. 29A, the original source used as a basis (a rat oral LD50 resulting in a TEEL-3 of 180 mg/m3) was not identified during research. Instead, the most current rat oral LD50 was selected as the TEEL basis.
• TEEL-1 = MW-adjusted TLV-TWA (soluble Fe)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (450 mg/kg)
This review generated TEEL-3 and TEEL-2 values that are more conservative than those in Rev. 29A, and a TEEL-1 which is consistent. In Rev. 29A, the original source used as a basis (a rat oral LD50 resulting in a TEEL-3 of 180 mg/m3) was not identified during research. Instead, the most current rat oral LD50 was selected as the TEEL basis.
References
https://cameochemicals.noaa.gov/chemical/8680
TLV-TWA: American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH, 2008, p. 35; via HSDB: https://pubchem.ncbi.nlm.nih.gov/source/hsdb/449
LDLo: Veterinary and Human Toxicology, 40,31,1998; National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 24380, Ferric Chloride. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Ferric-Chloride
Rat oral LD50: Gigiena i Sanitariya. For English translation, see HYSAAV., 39(5)(16), 1974; Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Ferric-Chloride
https://www.fishersci.com/msds?productName=AC217091000&produc