PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fluoroacetamide | 640-19-7 | 2811 |
4.01
4.08
4.05
7.01
7.00
11.00
4.07
5.10
4.11
|
|||||||||
| Formula | Synonyms | |||||||||||
| C2.H4.F.N.O | FLUOROACETAMIDE, 1081, 2-FLUOROACETAMIDE, ACETAMIDE, 2-FLUORO-, AFL 1081, ALPHA-FLUOROACETAMIDE, COMPOUND 1081, FAA, FLUORAKIL 100, FLUOROACETIC ACID AMIDE, FLUTRITEX 1, FUSSOL, MEGATOX, MONOFLUOROACETAMIDE, NAVRON, RODEX, YANOCK | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 77.07 | S | 250 | 0.001 | 25 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.53 | 5.8 | 24 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.17 | 1.8 | 7.6 |
Technical Basis
A review of available sources identified the following: a LOC and acute animal toxicity data (LC50, LD50) for oral and intraperitoneal routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. A mouse LC50 was selected as the TEEL-3 basis, and it was scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). The LOC was selected as the TEEL-2. The TEEL-1 was derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC (0.0058 g/m3)
• TEEL-3 = Mouse LC50 (550 mg/m3/4H)
This review generated TEEL-2 and TEEL-1 values consistent with those in Rev. 29A. In Rev. 29A, the TEEL-3 basis was also an LC50 (550 mg/m3) with an assumed duration of 2-hrs, while the current review confirmed the duration to be 4-hrs (240 minutes), resulting in a slightly higher TEEL-3 value when the ten Berge equation was applied.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC (0.0058 g/m3)
• TEEL-3 = Mouse LC50 (550 mg/m3/4H)
This review generated TEEL-2 and TEEL-1 values consistent with those in Rev. 29A. In Rev. 29A, the TEEL-3 basis was also an LC50 (550 mg/m3) with an assumed duration of 2-hrs, while the current review confirmed the duration to be 4-hrs (240 minutes), resulting in a slightly higher TEEL-3 value when the ten Berge equation was applied.
References
https://cameochemicals.noaa.gov/chemical/5002
Appendix C, pg. C-5, https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
Mouse LC50 (4H): Agricultural and Biological Chemistry., 31(1294), 1967. DOI: 10.1080/00021369.1967.10858963. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Fluoroacetamide.
https://pubchem.ncbi.nlm.nih.gov/source/hsdb/2880
https://www.haz-map.com/Agents/5347