PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Fosthietan 21548-32-3
15.00
7.01
8.00
4.07






Formula Synonyms
C6.H12.N.O3.P.S2 FOSTHIETAN, (DIETHOXYPHOSPHINYLIMINO)-1,3-DITHIETANE, 1,3-DITHIETAN-2-YLIDENEPHOSPHORAMIDIC ACID DIETHYL ESTER, 1,3-DITHIETANE, PHOSPHORAMIDIC ACID DERIV., 2-(DIETHOXYPHOSPHINYLIMINO)-1,3-DITHIETANE, AC 64475, ACCONEM, CL 64475, GEOFOS, IMIDOCARBONIC ACID, PHOSPHONODITHIO-, CYCLIC METHYLENE P,P-D, NEM-A-TAK, NEMATAK, PHOSPHONODITHIOIMI- DOCARBONIC ACID CYCLIC METHYLENE P,P-DIE, PHOSPHORAMIDIC ACID, 1,3 DITHIETAN-2-YLIDENE-, DIETHYL ESTER
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
241.28 L 250 0.0000065 25 1.3
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.43 4.7 28
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.044 0.48 2.8
Technical Basis
A review of available sources identified oral LD50 toxicity data for rat and mouse, and a Level of Concern (LOC). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The oral LD50 doses were evaluated as TEEL-3 sources, however, when considering the preferable LOC as the TEEL-2, the LD50 data resulted in TEEL-3 values < TEEL-2; therefore, these were not selected as the TEEL-3 basis. The LOC was selected as the TEEL-2. TEEL-1 and TEEL-3 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC (0.0047 g/m3)
• TEEL-3 = TEEL-2 x 6
This review generated TEEL values that are consistent with Rev. 29A*.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Fosthietan.
LOC. Appendix C, pg. C-5. https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
Rat oral LD50 (4700 μg/kg): Farm Chemicals Handbook., (C216), 1991. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Fosthietan.
Mouse oral LD50 (18 mg/kg): Proceedings of the British Insecticide and Fungicide Conference. V-8, 1961-75. For Publisher information, See PBCDDQ, 2(625), 1975. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Fosthietan.
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