PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Gluconic acid, D- 526-95-4
4.03
14.01
14.02
4.09
4.13





Formula Synonyms
C6.H12.O7
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
196.18 S 131 1.24
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
18 200 1200
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
2.2 25 150
Technical Basis
A review of available sources identified rat acute toxicity data (LD50) for oral and intraperitoneal routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred route toxicity data, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (6.06 g/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-1 basis was a TLV-TWA for particles not otherwise specified (Section 3.5.2), from which the TEEL-2 and TEEL-3 were derived (Table 3.5). The current TEEL-3 basis is a rat oral LD50 for D-gluconic acid, from which TEEL-2 and TEEL-1 were derived (Table 3.5).
References
Chemical information and rat intraperitoneal LD50 retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Gluconic-Acid
Rat oral LD50: https://echa.europa.eu/registration-dossier/-/registered-dossier/1957/7/3/2
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