PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Heptachlor epoxide; (Epoxyheptachlor) | 1024-57-3 | 2761 |
4.05
7.01
8.00
11.00
4.10
4.07
3.08
2.02
3.09
3.04
|
|||||||||
| Formula | Synonyms | |||||||||||
| C10H5Cl7O | HEPTACHLOR EPOXIDE, (.+-.)-CIS-HEPTACHLOR EPOXIDE, 1,4,5,6,7,8,8-HEPTACHLORO-2,3-EPOXY-3A,4,7,7A-TETRAHYDRO-4,7, 2,3,4,5,6,7,7-HEPTACHLORO-1A,1B,5,5A,6,6A-HEXAHYDRO-2,5-METH, 2,5-METHANO-2H-INDENO[1,2-B]OXIRENE, 2,3,4,5,6,7,7-HEPTACHLO, 2,5-METHANO-2H-OXIRENO(A)INDENE, 2,3,4,5,6,7,7-HEPTACHLORO-1, 4,7-METHANOINDAN, 1,4,5,6,7,8,8-HEPTACHLORO-2,3-EPOXY-3A,4,7, CIS-HEPTACHLOR EPOXIDE, ENT 25,584, ENT 25584, EPOXYHEPTACHLOR, GPKH EPOXIDE, HCE, HEPOX, HEPTACHLOR CIS-OXIDE, HEPTEPOXIDE, HEXAHYDRO-, HIPTACHLOR EPOXIDE, NCI-C06893, OXIRENO(A)INDENE, VELSICOL 53-CS-17, VELSICOL 53CS17 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 389.32 | 160 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.15 | 0.50 | 3.0 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.0094 | 0.031 | 0.19 |
Technical Basis
A review of available sources identified mouse and rat acute toxicity (LD50) for oral routes and OEL-TWAs (several countries). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-2 values were derived according to Table 3.5. The lowest reported OEL-TWA (Canada, South Korea, Belgium) was selected as the TEEL-1 basis.
• TEEL-1 = OEL-TWA (Belgium, Canada, South Korea; 0.05 mg/m3) x 3
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (15 mg/kg)
This review generated TEEL values consistent with Rev. 29A. The Rev. 29A and current TEEL-3 and TEEL-2 values, source, and methodology are also consistent. However, the Rev. 29A and current TEEL-1 sources are inconsistent. The Rev. 29A source, a TLV-TWA, was not found during the current review; instead, analysts selected the lowest OEL-TWA reported by several countries.
• TEEL-1 = OEL-TWA (Belgium, Canada, South Korea; 0.05 mg/m3) x 3
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (15 mg/kg)
This review generated TEEL values consistent with Rev. 29A. The Rev. 29A and current TEEL-3 and TEEL-2 values, source, and methodology are also consistent. However, the Rev. 29A and current TEEL-1 sources are inconsistent. The Rev. 29A source, a TLV-TWA, was not found during the current review; instead, analysts selected the lowest OEL-TWA reported by several countries.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Epoxyheptachlor.
Gigiena i Sanitariya. For English translation, see HYSAAV., 52(2)(93), 1987. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Epoxyheptachlor.
OEL-TWA; https://ilv.ifa.dguv.de/limitvalues/30806.