PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hexamethyleneimine | 111-49-9 | 2493 |
14.02
11.00
7.00
4.10
14.01
11.01
4.07
7.01
|
|||||||||
| Formula | Synonyms | |||||||||||
| C6.H13.N | HEXAMETHYLENEIMINE, 1-AZACYCLOHEPTANE, AZACYCLOHEPTANE, G 0, G 0 (AMINE), HEXAHYDRO-1H-AZEPINE, HEXAHYDROAZEPINE, HEXAMÉTHYLÈNEIMINE (DOT FRENCH), HEXAMETHYLENIMINE, HEXAMETILENIMINA (DOT SPANISH), HOMOPIPERIDINE, PERHYDROAZEPINE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 99.2 | L | 138 | 8.09 | 25 | 0.8643 @ 22°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.6 | 18 | 110 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.39 | 4.4 | 27 |
Technical Basis
A review of available sources identified the following: mouse and rat LC50 animal toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Inhalation exposures were scaled to 60-minute equivalents using the ten Berge equation (Section 3.3.4). The rat LC50 was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (2450 mg/m3/4H)
This review generated TEEL values that are lower than those in Rev. 29A. The Rev. 29A TEEL-3 basis was a mouse LC50 (10,800 mg/m3/2H), while the current TEEL-3 is a more preferred species inhalation dose (rat > mouse, Table 3.1,) a rat LC50 (2,450 mg/m3/4H). The Rev. 29A and current TEEL-2 and TEEL-1 values were derived using the same methodology (Table 3.5).
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (2450 mg/m3/4H)
This review generated TEEL values that are lower than those in Rev. 29A. The Rev. 29A TEEL-3 basis was a mouse LC50 (10,800 mg/m3/2H), while the current TEEL-3 is a more preferred species inhalation dose (rat > mouse, Table 3.1,) a rat LC50 (2,450 mg/m3/4H). The Rev. 29A and current TEEL-2 and TEEL-1 values were derived using the same methodology (Table 3.5).
References
https://pubchem.ncbi.nlm.nih.gov/compound/Hexamethyleneimine.
https://haz-map.com/Agents/5527