PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hexanol, 2-; (2-Hydroxyhexane) | 626-93-7 |
11.01
7.00
7.01
8.00
4.01
16.02
3.11
15.01
|
||||||||||
| Formula | Synonyms | |||||||||||
| C6.H14.O | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 102.2 | L | 139 | 0.814 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 8.8 | 97 | 580 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 2.1 | 23 | 140 |
Technical Basis
A review of available sources identified the following: rat LC50 and LD50 toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The rat LC50 was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were calculated according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LC50 (>21 mg/L/1H)
This review generated TEEL values that are more conservative that Rev. 29A. The Rev. 29A TEEL-3 basis was an assumed HHR=2, while the current basis is an acute inhalation toxicity data. The Rev. 29A and current TEEL-2 and TEEL-1 values were derived using the same methodology, with differences due to the change in TEEL-3.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LC50 (>21 mg/L/1H)
This review generated TEEL values that are more conservative that Rev. 29A. The Rev. 29A TEEL-3 basis was an assumed HHR=2, while the current basis is an acute inhalation toxicity data. The Rev. 29A and current TEEL-2 and TEEL-1 values were derived using the same methodology, with differences due to the change in TEEL-3.
References
https://pubchem.ncbi.nlm.nih.gov/compound/2-Hexanol
https://echa.europa.eu/de/registration-dossier/-/registered-dossier/13265/7/3/1