PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Hydroxymethanesulfinic acid, monosodium salt; (Formaldehyde hydrosulfite) 149-44-0
4.00
3.00








Formula Synonyms
C.H4.O3.S.Na
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
119.1 S
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
6.0 66 400
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
1.2 14 82
Technical Basis
A review of available sources identified rat and mouse acute LD50 toxicity data for various routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route data, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2 g/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a mouse oral LD50, while the current basis is a more preferred species, a rat oral LD50 (rat > mouse, Section 3.3.4.). The Rev. 29A and current TEEL-2 and TEEL-1 methodologies remain consistent, with differences in values due to the change of the TEEL-3 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-formaldehydesulfoxylate
Rat oral LD50: Yakkyoku. Pharmacy., 31(959), 1980. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-formaldehydesulfoxylate
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