PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Isodrin 465-73-6
8.00
11.00
15.02
4.08
7.01
4.05
4.06
4.10
4.07
3.10
Formula Synonyms
C12H8Cl6 ISODRIN, 1,2,3,4,10,10-HEXACHLORO-1,4,4A,5,8,8A- HEXAHYDRO-ENDO,ENDO-, 1,2,3,4,10,10-HEXACHLORO-1,4,4A,5,8,8A-HEXAHYDRO-1,4, 1,4:5,8-DIMETHANONAPHTHALENE, 1,2,3,4,10,10-HEXACHLORO- 1,4,, 1,4:5,8-DIMETHANONAPHTHALENE, 1,2,3,4,10,10-HEXACHLORO-1,4,4, 1,4:5,8-DIMETHANONAPHTHALENE, 1,2,3,4,10,10-HEXACHLORO-1,4,4, 1,4:5,8-DIMETHANONAPHTHALENE, 1,2,3,4,10,10-HEXACHLORO-1,4,4, 5,8- ENDO,ENDO-DIMETHANONAPHTHALENE, COMPOUND 711, ENT 19,244, EXPERIMENTAL INSECTICIDE 711, ISODRIN (INSECTICIDE), SD 3418
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
364.9 S 344 0.00001 25
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.64 7.0 42
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.043 0.47 2.8
Technical Basis
A review of available sources identified rat and mouse oral LD50 toxicity data and a Level of Concern (LOC). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The oral LD50 doses were evaluated as TEEL-3 sources, however, when considering the preferable LOC as the TEEL-2, the LD50 data resulted in TEEL-3 values < TEEL-2; therefore, these were not selected as the TEEL-3 basis. The LOC was selected as the TEEL-2. TEEL-1 and TEEL-3 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC (0.007 g/m3)
• TEEL-3 = TEEL-2 x 6
This review generated TEEL values consistent with Rev. 29A*.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Isodrin-_insecticide
LOC: Retrieved from Exhibit C-1 (page C-5); https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
Rat and mouse oral LD50 toxicity data: Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 2134. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Isodrin-_insecticide.
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