PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lanthanum hydroxide | 14507-19-8 |
11.01
14.01
14.02
|
||||||||||
| Formula | Synonyms | |||||||||||
| La(OH)3 | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 189.92752 | S |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 12 | 130 | 790 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.5 | 17 | 100 |
Technical Basis
A review of available sources did not identify exposure limits or acute toxicity data for lanthanum hydroxide. Safety data sheets report GHS health hazard codes (H314, Category 1; H315, H319, H335, Category 2; Category 3) and an NPFA=1, indicating a low to mid-level health hazard. Additionally, toxicity data indicates that no rats died when exposed to a dose of > 2000 mg/kg. Considering this, analysts assumed an HHR=2 as the TEEL-3 basis (Section 3.4.5). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = HHR=2
This review generated PAC values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was an assumed HHR=3. Currently available information indicates this may be overly conservative; therefore, analysts assumed an HHR=2. The Rev. 29A and current TEEL-2 and TEEL-1 use the same methodology, with differences due to the change in TEEL-3.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = HHR=2
This review generated PAC values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was an assumed HHR=3. Currently available information indicates this may be overly conservative; therefore, analysts assumed an HHR=2. The Rev. 29A and current TEEL-2 and TEEL-1 use the same methodology, with differences due to the change in TEEL-3.
References
Chemical information: https://comptox.epa.gov/dashboard/chemical/details/DTXSID5065778
Rat oral LD: https://chem.echa.europa.eu/100.034.994/dossier-view/8c371074-dee0-43d4-b0d2-8da2c579b240/IUC5-5bd920f7-e1ee-4d07-b8df-91279d66c0fb_1bd6a662-a984-4ccd-9b39-44495407602b?searchText=14507-19-8
Chemical Book SDS reporting GHS health hazards: https://www.chemicalbook.com/msds/lanthanum-hydroxide.htm