PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lithium sulfate | 10377-48-7 |
4.08
4.05
7.01
8.00
7.00
11.00
4.07
3.02
|
||||||||||
| Formula | Synonyms | |||||||||||
| Li2O4S | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 109.94 | S | 859 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.29 | 3.2 | 120 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.064 | 0.71 | 27 |
Technical Basis
A review of available data sources identified the following: a rat oral LD50 and a human (female) oral TDLo. Analysts explored this toxicity data, applying Tables 3.1, and 3.4 from the handbook to derive TEEL-3 (LD50) and TEEL-2 (TDLo) values. A TEEL-1 was derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = Human (female) oral TDLo (6 mg/kg, coma toxic endpoint)
• TEEL-3 = Rat oral LD50 (613 mg/kg)
The current TEEL-3 concurs with Rev. 29A, while TEEL-2 and TEEL-1 are more conservative. Previously, these limits were derived from TEEL-3 using the adjustment factors in Table 3.5, while the current approach is the use independent data for the TEEL-2 basis.
• TEEL-1 = TEEL-2/11
• TEEL-2 = Human (female) oral TDLo (6 mg/kg, coma toxic endpoint)
• TEEL-3 = Rat oral LD50 (613 mg/kg)
The current TEEL-3 concurs with Rev. 29A, while TEEL-2 and TEEL-1 are more conservative. Previously, these limits were derived from TEEL-3 using the adjustment factors in Table 3.5, while the current approach is the use independent data for the TEEL-2 basis.
References
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:53474
Rat oral LD50: EHP, Environmental Health Perspectives., 106(Suppl) via PubChem: National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 66320, Lithium sulfate. https://pubchem.ncbi.nlm.nih.gov/compound/Lithium-sulfate
Human (female) oral TDLo: Journal of Toxicology, Clinical Toxicology., 25(81), 1987 [PMID:3586088] via PubChem: National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 66320, Lithium sulfate. https://pubchem.ncbi.nlm.nih.gov/compound/Lithium-sulfate