PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Magnesium chloride | 7786-30-3 |
4.01
11.01
4.08
4.05
7.01
8.00
7.00
11.00
4.06
7.10
|
||||||||||
| Formula | Synonyms | |||||||||||
| Cl2Mg | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 95.21 | S | 714 | 1412 | 2.325 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 3.3 | 36 | 210 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.85 | 9.2 | 54 |
Technical Basis
A review of available sources identified rat and mouse LD50 toxicity data for various routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Two rat oral LD50 doses (1085 mg/kg, 2800 mg/kg) were evaluated for the TEEL-3 basis, and the most conservative dose was selected as the TEEL-3 basis. TEEL-1 and TEEL-2 values were derived according to Table 3.5
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (1085 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat oral LD50 that was identified in this review; however, analysts found and used a more conservative dose. The Rev. 29A TEEL-2 was a mouse intraperitoneal TDLo that was not found in the current review; instead, it was derived according from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-2.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (1085 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat oral LD50 that was identified in this review; however, analysts found and used a more conservative dose. The Rev. 29A TEEL-2 was a mouse intraperitoneal TDLo that was not found in the current review; instead, it was derived according from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-2.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium-Chloride.
Rat oral LD50 (2800 mg/kg): Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 2078. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium-Chloride.
Rat oral LD50 (1085 mg/kg): SIAM Initial Assessment Profile for Magnesium Chloride. 9-21, April 2011. Retrieved from: https://hpvchemicals.oecd.org/ui/handler.axd?id=a70bb73c-12f8-447d-90d3-24535bde3819