PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Magnesium sulfate heptahydrate 10034-99-8
4.07
7.01
Formula Synonyms
Mg.S.O4.7H2O
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
246.51 S 1.68
PAC Values
PAC Values (Original Units: ppm)
PAC-1 PAC-2 PAC-3
1.2 13 81
Converted PAC Values (mg/m3)
PAC-1 PAC-2 PAC-3
12 130 820
Technical Basis
A review of available data sources identified the following: LD50 toxicity data for oral and dermal exposures. The sources used for this review were evaluated using the guidelines for calculating equivalent values in the TEEL Handbook. Species and route are ranked according to the preferences stated in Section 3.3.2, while the data source was evaluated according to the hierarchy listed in Table 3.1. Rat oral LD50 toxicity data was determined to be the most preferred source and it was selected as the starting point to estimate a TEEL-3. This estimate was more conservative that the existing PAC-3 data from Rev 29A. The sets of toxicity data used for this estimation was from non-HSDB/SAX/RTECS, although they were sourced from reputable chemistry informational websites (Sigma Aldrich).
• TEEL-1 = TEEL-2 / 11
• TEEL-2 = TEEL-3 / 6
• TEEL-3 = Rat oral LD50 (>2000 mg/kg)
This review generated TEEL values that were more conservative than those in Rev. 29A and thus it is recommended that the new PAC values be changed.
References
SigmaAldrich SDS (4/27/2021): https://www.sigmaaldrich.com/US/en/sds/sigald/230391
ThermoFisher Scientific SDS (2/4/2014): https://www.fishersci.com/store/msds?partNumber=M63500&countryCode=US&language=en
EMD Millipore SDS (6/26/2023): https://www.emdmillipore.com/US/en/product/msds/MDA_CHEM-105886?Origin=PDP
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.