PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mastic (resin) | 61789-92-2 |
4.07
3.10
3.05
3.08
3.09
3.02
5.10
|
||||||||||
| Formula | Synonyms | |||||||||||
| [Unspecified] | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 0 | S |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.3 | 14 | 85 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0 | 0 | 0 |
Technical Basis
A review of available data sources identified the following: LDLo1 and LD502 toxicity data for oral and dermal exposures. The data is limited for this compound, therefore similar chemicals were also evaluated, including α-pinene, the main component of mastic resin. Exposure and toxicity data available were available for α-pinene and resulted in conservative TEEL values. After reviewing this evaluation and considering that mastic resin is not classified as a hazardous substance, this approach was not selected. Instead, toxicity data for the chemical of interest were evaluated for their relative preference ranking3.
The most preferred species and route of rat oral LDLo data was selected as the starting point to estimate a TEEL-3. TEEL-2 and TEEL-1 values were developed with adjustment factors were used to fill the gaps (Table 3.5).
• TEEL-1 = TEEL-2 / 11
• TEEL-2 = TEEL-3 / 6
• TEEL-3 = Estimated from rat, oral LDLo (5 g/kg)
This review generated TEEL values are consistent with those found in Rev 29A.
The most preferred species and route of rat oral LDLo data was selected as the starting point to estimate a TEEL-3. TEEL-2 and TEEL-1 values were developed with adjustment factors were used to fill the gaps (Table 3.5).
• TEEL-1 = TEEL-2 / 11
• TEEL-2 = TEEL-3 / 6
• TEEL-3 = Estimated from rat, oral LDLo (5 g/kg)
This review generated TEEL values are consistent with those found in Rev 29A.
References
Rat oral LDLo: Food and Chemical Toxicology., 30(71S), 1992; via PubChem: https://pubchem.ncbi.nlm.nih.gov/substance/135306537#section=Acute-Effects
Rabbit skin LD50 (listed as a lower limit): Food and Chemical Toxicology., 30(71S), 1992; via PubChem: https://pubchem.ncbi.nlm.nih.gov/substance/135306537#section=Acute-Effects
Species and route are ranked according to the preferences stated on pg. 12-13 of the DOE handbook (exposure type is ranked from Table 3.1.)