PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mercaptoethanol, 2- | 60-24-2 | 2966 |
14.01
11.00
7.01
4.08
4.10
4.07
8.00
15.02
3.08
4.01
|
|||||||||
| Formula | Synonyms | |||||||||||
| C2.H6.O.S | THIOGLYCOL, 1-ETHANOL-2-THIOL, 1-HYDROXY-2-MERCAPTOETHANE, 1-MERCAPTO-2-HYDROXYETHANE, 2-HYDROXY-1-ETHANETHIOL, 2-HYDROXYETHANETHIOL, 2-HYDROXYETHYL MERCAPTAN, 2-ME, 2-MERCAPTO-1-ETHANOL, 2-MERCAPTOETHANOL, 2-MERCAPTOETHYL ALCOHOL, 2-THIOETHANOL, BETA-HYDROXYETHANETHIOL, BETA-HYDROXYETHYLMERCAPTAN, BETA-MERCAPTOETHANOL, EMERY 5791, ETHYLENE GLYCOL, MONOTHIO-, HYDROXYETHYL MERCAPTAN, MERCAPTOETHANOL, MONOTHIOETHYLENE GLYCOL, MONOTHIOETHYLENEGLYCOL, MONOTHIOGLYCOL, THIOETHYLENE GLYCOL, THIOGLYCOL (DOT FRENCH), THIOMONOGLYCOL, TIOGLICOL (DOT SPANISH), UN2966, USAF EK-4196 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 78.14 | L | 1 | 20 | 1.1168 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.60 | 2.3 | 14 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.9 | 7.4 | 45 |
Technical Basis
A review of available sources identified the following: WEEL-TWA, LC50, LCLo, and LD50 toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Inhalation exposures were scaled to 60-minute equivalents using the ten Berge equation (Section 3.3.4). The rat 8-hr LCLo was selected as the TEEL-3 basis because the LC50 exposure duration was not reported and could not be confirmed. The TEEL-2 was derived according to Table 3.5. The WEEL-TWA was selected as the TEEL-1 basis.
• TEEL-1 = WEEL-TWA x 3 (0.2 ppm)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat 8-hr LCLo (250 ppm)
This review generated TEEL-3 and TEEL-2 values that are inconsistent with Rev. 29A. The TEEL-3 is more conservative due to a change in basis from an LC50 to an LCLo due to missing information (Section 3.3.1). The Rev. 29A TEEL-2 basis was a rat oral TDLo, which was not found during current research. The current TEEL-2 was derived from the TEEL-3. The current and Rev. 29A TEEL-1 method and values are consistent.
• TEEL-1 = WEEL-TWA x 3 (0.2 ppm)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat 8-hr LCLo (250 ppm)
This review generated TEEL-3 and TEEL-2 values that are inconsistent with Rev. 29A. The TEEL-3 is more conservative due to a change in basis from an LC50 to an LCLo due to missing information (Section 3.3.1). The Rev. 29A TEEL-2 basis was a rat oral TDLo, which was not found during current research. The current TEEL-2 was derived from the TEEL-3. The current and Rev. 29A TEEL-1 method and values are consistent.
References
Union Carbide Data Sheet., 3/23/1973; National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 1567, Beta-Mercaptoethanol. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Beta-Mercaptoethanol
https://haz-map.com/Agents/3119
https://tera.org/OARS/