PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Methacrolein diacetate; (Acetic acid, 2-methyl-2-propene-1,1-diol diester) | 10476-95-6 |
14.01
14.02
4.01
4.05
7.01
7.00
|
||||||||||
| Formula | Synonyms | |||||||||||
| C8H12O4 | METHACROLEIN DIACETATE, 2-PROPENE-1,1- DIOL, 2-METHYL-, DIACETATE, ACETIC ACID, 2-METHYL-2-PROPENE-1,1-DIOL DIESTER | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 172.2 | L | 191 | 0.35 | 25 | 1.051 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.040 | 0.44 | 2.7 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.28 | 3.1 | 19 |
Technical Basis
A review of available sources acute toxicity data (LCLo, LD50, LDLo) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred route, a 4-hour rat LC¬Lo, was select as the TEEL-3 basis and scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LCLo (62 ppm/4H)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a 60-minute rat LCLo not found during the current review; instead, the current TEEL-3 basis is a scaled 4-hour rat LCLo. The Rev. 29A and current TEEL-2/TEEL-1 values were derived using the same methodology (Table 3.5), with differences due to the change in TEEL-3.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LCLo (62 ppm/4H)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a 60-minute rat LCLo not found during the current review; instead, the current TEEL-3 basis is a scaled 4-hour rat LCLo. The Rev. 29A and current TEEL-2/TEEL-1 values were derived using the same methodology (Table 3.5), with differences due to the change in TEEL-3.
References
American Industrial Hygiene Association Journal., 30(470), 1969 [PMID:5823428]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Methacrolein-diacetate.