PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Methyl 2-cyanoacrylate; (Permabond 910 adhesive) 137-05-3
11.01
15.01
14.02
5.00
4.11
4.01
Formula Synonyms
C5-H5-N-O2 METHYL 2-CYANOACRYLATE, 2-CYANO-2-PROPENOIC ACID METHYL ESTER, 2-CYANOACRYLIC ACID METHYL ESTER, 2-CYANOACRYLIC ACID, METHYL ESTER, ACRYLIC ACID, 2-CYANO-, METHYL ESTER, AD/HERE, ADHERE, ALPHA-CYANOACRYLIC ACID METHYL ESTER, CA 7, CA 7 (ADHESIVE), CEMEDINE 3000, CEMEDINE 3000 TYPE-II, CEMEDINE 3000DX, COAPT, CYANOBOND 5000, CYANOBOND SS, CYANOLIT, EASTMAN 910, EASTMAN 910 ADHESIVE, EASTMAN 910 MONOMER, EASTMAN 910 SUPER GLUE, FIMOFIX P 1048, MECRILAT, MECRILATE, MECRYLATE, METHYL 2-CYANO-2-PROPENOATE, METHYL ALPHA-CYANOACRYLATE, METHYL CYANOACRYLATE, METHYL ESTER OF 2-CYANOACRYLIC ACID, METHYL-ALPHA-CYANOACRYLATE, SICOMET 7000, THREE BOND 1701
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
111.11 L -22.5 200.5 0.2 25 1.1012
PAC Values
PAC Values (Original Units: ppm)
PAC-1 PAC-2 PAC-3
0.60 0.85 5.1
Converted PAC Values (mg/m3)
PAC-1 PAC-2 PAC-3
2.7 3.9 23
Technical Basis
A review of available sources identified acute rat and guinea pig toxicity data (LD50, LC50), and exposure limits (TWAs, STELs). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred route toxicity data, a rat LC50, was selected as the TEEL-3 basis and was scaled to 60-minute equivalent using the ten Berge equation (Section 3.3.4). The TEEL-2 values were derived according to Table 3.5. Although available STELs were considered as a TEEL-1 basis, they resulted in a TEEL-1 > TEEL-2; instead, the TLV-TWA was selected as the TEEL-1 basis.
• TEEL-1 = TLV-TWA (0.2 ppm) x 3
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (101 ppm/6H)
This review generated TEEL values consistent with Rev. 29A.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-2-cyanoacrylate.
Exposure limits (TLV-TWA) retrieved from: https://www.osha.gov/chemicaldata/252
Rat LC50: Documentation of the Threshold Limit Values and Biological Exposure Indices, 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986, 6(965), 1991. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-2-cyanoacrylate.
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.