PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Methylene diphenyl diisocyanate; (Diphenylmethane diisocyanate; MDI) | 101-68-8 | 2489 |
15.01
4.01
11.01
4.08
7.01
11.00
4.02
4.07
10.00
9.00
|
|||||||||
| Formula | Synonyms | |||||||||||
| C15H10N2O2 | DIPHENYLMETHANE-4,4^-DIISOCYANATE, 1,1'-METHYLENEBIS[4-ISOCYANATOBENZENE], 1,1-METHYLENEBIS(4-ISOCYANATOBENZENE), 4,4'-BIS(ISOCYANATOPHENYL)METHANE, 4,4'-DIISOCYANATODIPHENYLMETHANE, 4,4'-DIPHENYLMETHANE DIISOCYANATE, 4,4'-MDI, 4,4'-METHYLENEBIS(ISOCYANATOBENZENE), 4,4'-METHYLENEBIS(PHENYL ISOCYANATE), 4,4'-METHYLENEDI(PHENYL ISOCYANATE), 4,4'-METHYLENEDI-P-PHENYLENE DIISOCYANATE, 4,4'-METHYLENEDIPHENYL DIISOCYANATE, 4,4'-METHYLENEDIPHENYLDIISOCYANATE, 4,4'-METHYLENEDIPHENYLENE ISOCYANATE, 4,4'DIISOCYANATODIPHENYLMETHANE, 4,4-DIISOCIANATO DE DIFENILMETANO (DOT SPANISH), BENZENE, 1,1'-METHYLENEBIS(4-ISOCYANATO)- (9CI), BIS(1,4-ISOCYANATOPHENYL)METHANE, BIS(4-ISOCYANATOPHENYL)METHANE, BIS(P-ISOCYANATOPHENYL)METHANE, CARADATE 30, CARWINATE 125 M, DESMODUR 44, DI(4-ISOCYANATOPHENYL)METHANE, DIISOCYANATE DE DIPHÉNYLMÉTHANE-4,4' (DOT FRENCH), DIPHENYLMETHANE 4,4'-DIISOCYANATE, DIPHENYLMETHANE DIISOCYANATE, DIPHENYLMETHYLENE DIISOCYANATE, HYLENE M50, ISOCYANIC ACID, DIPHENYLMETHYLENE ESTER, ISOCYANIC ACID, METHYLENEDI-P-PHENYLENE ESTER, ISONATE 125M, ISONATE 125MF, MDI, METHYLENE BIS(4-PHENYL ISOCYANATE), METHYLENE DI-P-PHENYLENE ESTER OF ISOCYANIC ACID, METHYLENEBIS(4-ISOCYANATOBENZENE), METHYLENEBIS(4-PHENYL ISOCYANATE), METHYLENEBIS(4-PHENYLENE ISOCYANATE), METHYLENEBIS(P-PHENYL ISOCYANATE), METHYLENEBIS(P-PHENYLENE ISOCYANATE), METHYLENEBIS(PHENYLISOCYANATE), METHYLENEBIS-P-PHENYLENE DIISOCYANATE, METHYLENEBISPHENYLENE DIISOCYANATE, METHYLENEDI-P-PHENYLENE DIISOCYANATE, METHYLENEDI-P-PHENYLENE ISOCYANATE, MULTRATHANE M, NACCONATE 300, NCI-C50668, NOCCONATE 300, P,P'-DIPHENYLMETHANE DIISOCYANATE, P,P'-METHYLENEBIS(PHENYL ISOCYANATE), VILRATHANE 4300 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 250.25 | S | 37 | 25 | 1.197 @ 70°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.15 | 5.0 | 55 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.015 | 0.49 | 5.4 |
Technical Basis
A review of available sources identified the following: ERPG-3, ERPG-2, TLV-TWA, REL-TWA, PEL-TWA and IDLH exposure limits, and numerous acute toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. The ERPG-3 was selected as the TEEL-3 and the ERPG-2 was selected as the TEEL-2. The TLV-TWA was selected as the TEEL-1 basis.
• TEEL-1 = TLV-TWA (0.05 mg/m3) x 3
• TEEL-2 = ERPG-2 (5 mg/m3)
• TEEL-3 = ERPG-3 (55 mg/m3)
This review generated TEEL-2 and TEEL-3 values inconsistent with Rev. 29A. The TEEL-3 and TEEL-2 remain the ERPG-3 and ERPG-2 values. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 basis is an exposure limit (TLV-TWA).
• TEEL-1 = TLV-TWA (0.05 mg/m3) x 3
• TEEL-2 = ERPG-2 (5 mg/m3)
• TEEL-3 = ERPG-3 (55 mg/m3)
This review generated TEEL-2 and TEEL-3 values inconsistent with Rev. 29A. The TEEL-3 and TEEL-2 remain the ERPG-3 and ERPG-2 values. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 basis is an exposure limit (TLV-TWA).
References
ERPGs: https://cameochemicals.noaa.gov/chemical/8588
TLV-TWA: https://www.osha.gov/chemicaldata/23