PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Methylphenylthiourea, 2-; (o-Tolyl thiourea) 614-78-8
4.00
3.00
Formula Synonyms
C8H10N2S THIOUREA, (2-METHYLPHENYL)-, (2-METHYLPHENYL)THIOUREA, 1-(2-METHYLPHENYL)THIOUREA, 1-O-TOLYL-2-THIOUREA, 2-TOLYLTHIOUREA, N-(2-METHYLPHENYL)THIOUREA, N-(O-TOLYL)THIOUREA, O-TOLYL THIOUREA, O-TOLYLTHIOUREA, UREA, 2-THIO-1-O-TOLYL-
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
166.26 S 0.000002 25
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
4.5 50 300
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.66 7.4 44
Technical Basis
A review of available sources identified exposure limits (LOC) and mouse and rat acute toxicity data (LD50, LDLo) for intraperitoneal and oral routes. Reported GHS health hazard ratings (H319, Category 2; H302, Category 3) indicate a mid-level health hazard, approximately equivalent to an HHR=2 (TEEL-3 = 790 mg/m3). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The LOC was selected as the TEEL-2. Acute toxicity was evaluated; however, the resultant TEEL-3 values were significantly more conservative than an HHR=2. Considering this, analysts instead derived the TEEL-3 and TEEL-1 according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = LOC (0.05 g/m3)
• PAC-3 = TEEL-3 = TEEL-2 x 6
This review generated PAC values consistent with Rev. 29A*.
References
Chemical information, GHS health hazard and acute toxicity data retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/2787703
LOC. Appendix C, pg. C-9. https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.