PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Methylpyrrolidine; (Methylpyrrolidine, 1-) 120-94-5
11.01
15.01
15.02
Formula Synonyms
C5-H11-N
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
85.15 L -90 80.5 0.8054
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.58 6.4 39
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.17 1.8 11
Technical Basis
A review of available sources identified mouse and rat acute exposure toxicity studies (routes of exposure include intraperitoneal, intravenous, inhalation). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Although an inhalation is the most preferred route, the ECHA LC50 record could not be verified as a reliable source. Instead, the most preferred route, a mouse intraperitoneal LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Mouse intraperitoneal LD50 (178 mg/kg)
This review generated TEEL values that are consistent with Rev. 29A*.
References
Mouse intraperitoneal LD50. Journal of Pharmacology and Experimental Therapeutics., 88(82), 1946. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/1-Methylpyrrolidine
Rat LC50. Retrieved from: https://echa.europa.eu/de/registration-dossier/-/registered-dossier/11871/7/3/
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.