PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nicotinamide | 98-92-0 |
15.01
4.01
11.01
15.02
4.05
7.01
8.00
11.00
4.07
4.03
|
||||||||||
| Formula | Synonyms | |||||||||||
| C6.H6.N2.O | NICOTINAMIDE, 3-(AMINOCARBONYL)PYRIDINE, 3-AMIDOPYRIDINE, 3-CARBAMOYLPYRIDINE, 3-PYRIDINE CARBOXYLIC ACID AMIDE, 3-PYRIDINECARBOXYLIC ACID AMIDE, ACID AMIDE, AMIDE PP, AMINICOTIN, AMIXICOTYN, AMNICOTIN, AUSTROVIT PP, BENICOT, BETA-PYRIDINECARBOXAMIDE, DELONIN AMIDE, DIPEGYL, DIPIGYL, ENDOBION, FACTOR PP, HANSAMID, INOVITAN PP, M-(AMINOCARBONYL)PYRIDINE, NAM, NANDERVIT-N, NI-NICOTYL, NIACEVIT, NIACINAMIDE, NIAMIDE, NIAVIT PP, NICAMIDE, NICAMINA, NICAMINDON, NICASIR, NICOBION, NICOFORT, NICOGEN, NICOMIDOL, NICOSAN 2, NICOSYLAMIDE, NICOTA, NICOTAMIDE, NICOTILAMIDE, NICOTILILAMIDO, NICOTINE ACID AMIDE, NICOTINIC ACID AMIDE, NICOTINIC AMIDE, NICOTOL, NICOTYLAMIDE, NICOVEL, NICOVIT, NICOVITINA, NICOVITOL, NICOZYMIN, NIKO-TAMIN, NIOCINAMIDE, NIOZYMIN, PAPULEX, PELMIN, PELMINE, PELONIN AMIDE, PP-FAKTOR, PYRIDINE-3-CARBOXYLIC ACID AMIDE, SAVACOTYL, VI-NICOTYL, VITAMIN B, VITAMIN B3, VITAMIN PP, WITAMINA PP | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 122.14 | S | 0.00042 | 25 | 1.4 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 10 | 120 | 690 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 2.0 | 24 | 140 |
Technical Basis
A review of available sources identified LD50 (mouse, rat) toxicity data. Data sources were evaluated according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (3,500 mg/kg)
This review generated TEEL-3 values consistent with Rev. 29A. The current TEEL-2 and TEEL-1 values are less conservative than Rev. 29A. The Rev. 29A TEEL-2 basis, a mouse intraperitoneal TDLo was not found during current research. The differences in TEEL-1 are due to the changes in TEEL-2.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (3,500 mg/kg)
This review generated TEEL-3 values consistent with Rev. 29A. The current TEEL-2 and TEEL-1 values are less conservative than Rev. 29A. The Rev. 29A TEEL-2 basis, a mouse intraperitoneal TDLo was not found during current research. The differences in TEEL-1 are due to the changes in TEEL-2.
References
Prehled Prumyslove Toxikologie; Organicke Latky, Marhold, J., Prague, Czechoslovakia, Avicenum, 1986, (1390), 1986; National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 936, Nicotinamide. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Nicotinamide.