PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nicotine; (Pyridine, (S)-3-(1-methyl-2-pyrrolidinyl)-); (Includes DL-Nicotine, 22083-74-5) | 54-11-5 | 1654 |
15.01
11.01
14.02
8.00
6.00
4.05
7.01
4.08
7.00
4.01
|
|||||||||
| Formula | Synonyms | |||||||||||
| C10H14N2 | NICOTINE, NICOTINE AND SALTS, (-)-3-(1-METHYL-2-PYRROLIDYL)PYRIDINE, (-)-NICOTINE, (S)-(-)-NICOTINE, (S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE, (S)-NICOTINE, FLUX MAAG, L-NICOTINE, NICODERM, NICONIL, NICOTIN, NICOTINELL, PYRIDINE, 3-(1-METHYL-2-PYRROLIDINYL)-, (S)-, XL ALL INSECTICIDE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 162.26 | L | -79 | 247.3 | 1.0092 @ 20°C | 7000 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.15 | 3.5 | 35 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.023 | 0.53 | 5.3 |
Technical Basis
A review of available sources identified exposure limits (IDLH, LOC, TWAs) and acute toxicity data (LDLo, LD50) for numerous species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were evaluated using factors in Tables 3.2, 3.3, and 3.4. The IDLH (1990) was selected as the TEEL-3. The LOC was selected as the TEEL-2. The TLV-TWA was selected as the TEEL-1 basis.
• PAC-1 = TEEL-1 = TLV-TWA (0.05 mg/m3) x 3
• PAC-2 = TEEL-2 = LOC (0.0035 g/m3)
• PAC-3 = TEEL-3 = IDLH (1990)
This review generated PAC-3 and PAC-2 values consistent with Rev. 29A. PAC-1 value is inconsistent; the Rev. 29A value was derived from the TEEL-2, while the current TEEL-1 basis is a TLV-TWA.
• PAC-1 = TEEL-1 = TLV-TWA (0.05 mg/m3) x 3
• PAC-2 = TEEL-2 = LOC (0.0035 g/m3)
• PAC-3 = TEEL-3 = IDLH (1990)
This review generated PAC-3 and PAC-2 values consistent with Rev. 29A. PAC-1 value is inconsistent; the Rev. 29A value was derived from the TEEL-2, while the current TEEL-1 basis is a TLV-TWA.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/89594
TLV-TWA: https://www.osha.gov/chemicaldata/396
LOC. Appendix C, pg. C-6. https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
IDLH: https://www.cdc.gov/niosh/idlh/54115.html