PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Niobium pentoxide; (Niobium(V) oxide) 1313-96-8
15.01
11.01
15.02
7.01
7.00
11.00
4.10
3.08
3.02
Formula Synonyms
Nb2O5
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
265.82 S 1500 4.6
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
3.6 40 240
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.33 3.7 22
Technical Basis
A review of available sources identified acute animal toxicity data (LD50, LC50). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route, a rat LC50, was selected as the TEEL-3 basis and scaled to 60-minute equivalent using the ten Berge equation (Section 3.3.4). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LC50 (5.45 mg/L/4H)
This review generated TEEL values inconsistent with those in Rev. 29A. The Rev. 29A basis was a mouse oral LD50, while the current basis is a more preferred species (rat > mouse) and route (LC50 > LD50). The Rev. 29A and current TEEL-2/TEEL-1 methodology are consistent, with differences in value due to the TEEL-3 basis change.
References
Mouse LD50; Hygiene and Sanitation, 32(10-12) (343), 1967. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/123105
Rat LC50. Retrieved from: https://echa.europa.eu/de/registration-dossier/-/registered-dossier/14981/7/3/3
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.