PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nonanenitrile; (1-Octyl cyanide) | 2243-27-8 |
4.00
3.00
|
||||||||||
| Formula | Synonyms | |||||||||||
| C9-H17-N | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 139.27 | L | -34.2 | 224.4 | 0.8178 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 3.4 | 37 | 220 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.60 | 6.5 | 39 |
Technical Basis
A review of limited sources identified a mouse oral LD50 which was selected as the TEEL-3 and evaluated using factors in Tables 3.2, 3.3, and 3.4. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Mouse oral LD50 (2059 mg/kg)
This review generated PAC values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-3 was a weight adjusted 1990 IDLH for cyanide compounds, while the current TEEL-3 basis is acute toxicity for nonanenitrile. The Rev. 29A and current TEEL-2 use the same methodology, with differences due to the change in TEEL-3. The Rev. 29A TEEL-1 basis was a weight adjusted MAK-TWA for cyanides, while the current TEEL-1 was derived from the TEEL-2 (Section 3.4.2).
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Mouse oral LD50 (2059 mg/kg)
This review generated PAC values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-3 was a weight adjusted 1990 IDLH for cyanide compounds, while the current TEEL-3 basis is acute toxicity for nonanenitrile. The Rev. 29A and current TEEL-2 use the same methodology, with differences due to the change in TEEL-3. The Rev. 29A TEEL-1 basis was a weight adjusted MAK-TWA for cyanides, while the current TEEL-1 was derived from the TEEL-2 (Section 3.4.2).
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Nonanenitrile
Mouse LD50 .Archives of Toxicology., 55(47), 1984 [PMID:6732504]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Nonanenitrile