PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asbestos, inlcudes: (Amosite, 12172-73-5, Ascarite, 81133-20-2, Chrysotile, 1332-21-4) | 1332-21-4 | 2212 |
1.00
10.00
11.00
4.06
3.07
3.02
3.11
15.01
|
|||||||||
| Formula | Synonyms | |||||||||||
| [Unspecified] | ASBESTOS, 4T04, 7N05, 7R-F9, 7RF10, ACTINOLITE, ACTINOLITE ASBESTOS, AMOSITE (CUMMINGTONITE-GRUNERITE), ANTHOPHYLLITE, ANTHOPHYLLITE ASBESTOS, ASBESTOS (FRIABLE), ASBESTOS FIBER, AT 7-1, BK 6-20, BP 3-50, BP 5-65, CALIDRIA HPP, CALIDRIA R-G 244, CAREY 4T, CHLOROBESTOS 25, CHRYSOTILE, CROCIDOLITE (RIEBECKITE), FAPM 410-120, FERODO C3C, FIBERS, MINERAL, ASBESTOS, HPO (MINERAL), K 6-20, LITAFLEX, M 3-60, M 4-5, M 5-60, M 6-40, MOUNTAIN CORK, MOUNTAIN LEATHER, MOUNTAIN WOOD, MTM, P 5-50, PRZH 2-30, SEPIOLEX 3, SEPIOLEX 5, SM 1 (MINERAL), SM 2 (MINERAL), T 135, TREMOLITE, TREMOLITE ASBESTOS | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 0 | S fibers |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.03 | 0.33 | 2.0 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0 | 0 | 0 |
Technical Basis
A review of limited available sources identified the following exposures: PEL-TWA, LDLo (Chrysotile asbestos, CASRN: 12001-29-5,) and TDLo for intraperitoneal routes. The toxicity data were not selected for TEEL estimates. As stated in the TEEL handbook, TDLo and LDLo are usually generated from a single data point and are therefore a less rigorously derived value than the PEL-STEL (See A-3). The PEL-STEL was selected as the TEEL-1 basis; the PEL-STEL was reported in units of fiber/mL, which were converted using a 1986 EPA estimate (see reference 3) TEEL-2 and TEEL-3 values were calculated from this TEEL-1 value, according to Table 3.5.
• TEEL-1 = PEL-STEL (1 fiber/mL; converted to 0.03 mg/m3, assuming 33 fibers/mL is approximately 1 mg/m3).
• TEEL-2 = TEEL-1 x 11
• TEEL-3 =TEEL-2 x 6
This review generated TEEL values that are more conservative than those in Rev. 29A. Revision 29A and the current TEELs have consistent methods (PEL-STEL derived TEELs,) however the current PEL-STEL value identified in research was lower, resulting in comparable, but lower TEELs.
• TEEL-1 = PEL-STEL (1 fiber/mL; converted to 0.03 mg/m3, assuming 33 fibers/mL is approximately 1 mg/m3).
• TEEL-2 = TEEL-1 x 11
• TEEL-3 =TEEL-2 x 6
This review generated TEEL values that are more conservative than those in Rev. 29A. Revision 29A and the current TEELs have consistent methods (PEL-STEL derived TEELs,) however the current PEL-STEL value identified in research was lower, resulting in comparable, but lower TEELs.
References
https://cameochemicals.noaa.gov/chemical/10531
https://www.osha.gov/chemicaldata/231
Conversion factor for fibers per volume estimates: Agency for Toxic Substances and Disease Registry (ATSDR). 2001. Toxicological profile for Asbestos. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, pg. 25, accessed from https://www.atsdr.cdc.gov/ToxProfiles/tp61-c3.pdf
Rat, intraperitoneal LDLo: American Journal of Pathology., 70(291), 1973 [PMID:4689512]; via PubChem: National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 25477, Chrysotile Asbestos. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Chrysotile-Asbestos
Mouse, intraperitoneal TDLo: TOXID9,124,2008; via NIOSH: https://www.cdc.gov/niosh-rtecs/CI62CCF8.html