PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Phenolphthalein 77-09-8
15.01
15.02
4.05
4.08
7.01
7.00
4.09
4.07
2.00
2.02
Formula Synonyms
C20H14O4
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
318.34 S 1.299
PAC Values
PAC Values (Original Units: ppm)
PAC-1 PAC-2 PAC-3
0.12 1.4 20
Converted PAC Values (mg/m3)
PAC-1 PAC-2 PAC-3
1.6 18 260
Technical Basis
A review of available sources was unable to identify exposure limits for this chemical, but toxicity data was available. The rat intraperitoneal LDLo data was selected as the TEEL-3 basis. The human, oral TDLo was selected as the TEEL-2 basis, because humans are the most preferred species (See Section 3.3.2.) The TEEL-1 value was calculated from this TEEL-2 value, in accordance with guidelines in the handbook (Table 3.5.)

TEEL-1 = TEEL-2/11
TEEL-2 = Human (male) oral TDLo (29 mg/kg; toxic endpoints: nausea/vomiting)
TEEL-3 = Rat intraperitoneal LDLo (500 mg/kg)

This review generated more conservative TEEL-1 and TEEL-2 values than those listed from Rev. 29A, which were based on rat intraperitoneal dosage. The current recommendation for TEEL-2 is based on a more preferred species and toxicity exposure route, while the TEEL-3 value remains consistent with Rev. 29A.
References
https://pubchem.ncbi.nlm.nih.gov/compound/4764#section=Adverse-Effects
https://chem.nlm.nih.gov/chemidplus/sid/0000077098
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.