PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phosmet | 732-11-6 |
6.00
8.00
15.01
4.05
11.00
4.01
4.02
7.01
7.00
4.08
|
||||||||||
| Formula | Synonyms | |||||||||||
| C11H12NO4PS2 | PHOSMET, (O,O-DIMETHYL-PHTHALIMIDIOMETHYLDITHIOPHOSPHATE), APPA, DECEMTHION, DECEMTHION EK 20, DECEMTHION P-6, DECEMTION, ENT 25,705, FOSMET, FTALOPHOS, IMIDAN, IMIDATHION, N-(MERCAPTOMETHYL)PHTHALIMIDE S-(O,O-DIMETHYL PHOSPHORODITHI, O,O-DIMETHYL S-(N-PHTHALIMIDOMETHYL) DITHIOPHOSPHATE, O,O-DIMETHYL S-(PHTHALIMIDOMETHYL) DITHIOPHOSPHATE, O,O-DIMETHYL S-PHTHALIMIDOMETHYL PHOSPHORODITHIOATE, ORBISECT, ORDATOX, PERCOLATE, PHOSPHORODITHIOIC ACID, O,O-DIMETHYL ESTER, S-ESTER WITH N-(, PHOSPHORODITHIOIC ACID, O,O-DIMETHYL S-PHTHALIMIDOMETHYL EST, PHOSPHORODITHIOIC ACID, S-((1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDO, PHTHALIMIDE, N-(MERCAPTOMETHYL)-, S-ESTER WITH O,O-DIMETHYL, PHTHALIMIDOMETHYL O,O-DIMETHYL PHOSPHORODITHIOATE, PHTHALOPHOS, PMP, PMP (PESTICIDE), PORECT, PROLATE, R 1504, S-PHTHALIMIDOMETHYL O,O-DIMETHYL PHOSPHORODITHIOATE, SAFIDON, SIMIDAN, SMIDAN, STARBAR GX 118, STAUFFER R 1504 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 317.33 | S | 71.9 | 0.00054 | 25 | 1.03 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.049 | 0.54 | 2.4 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.0038 | 0.042 | 0.18 |
Technical Basis
A review of available sources identified several acute toxicity data (LC50, LD50, LDLo, TCLo) for various routes and species, and exposure limits (OEL-STEL, OEL-TWA, LOC). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Inhalation exposures were scaled to 60-minute equivalents using the ten Berge equation (Section 3.3.4). The most preferred data and exposure type, a 4-hour rat LC50, was selected as the TEEL-3 basis. The high priority LOC was selected as the TEEL-2. The OEL-STEL and OEL-TWA (Romania) were evaluated for the TEEL-1 basis but resulted in TEEL-1 > TEEL-2 and/or TEEL-3 and were therefore not selected for TEEL development. Instead, the TEEL-1 value was derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = LOC (0.00054 gm/m3)
• PAC-3 = TEEL-3 = Rat LC50 (54 mg/m3 /4H)
This review generated PAC-1 and PAC-2 values consistent with Rev. 29A and a PAC-3 value inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was also a rat LC50; however, the current TEEL-3 rat C50 is a lower dose. The TEEL-2 and TEEL-1 values, source, and methodology are consistent.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = LOC (0.00054 gm/m3)
• PAC-3 = TEEL-3 = Rat LC50 (54 mg/m3 /4H)
This review generated PAC-1 and PAC-2 values consistent with Rev. 29A and a PAC-3 value inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was also a rat LC50; however, the current TEEL-3 rat C50 is a lower dose. The TEEL-2 and TEEL-1 values, source, and methodology are consistent.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Phosmet.
OELs: https://ilv.ifa.dguv.de/limitvalues/49971
Rat LC50: Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, -(59), 1982. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Phosmet.
LOC: Appendix C (page C-7): https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf