PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polychlorinated biphenyl (Aroclor 1232); (Chlorodiphenyl (32% Cl)) | 11141-16-5 | 2315 |
15.01
11.01
15.02
4.10
3.05
7.11
3.10
3.07
3.06
5.00
|
|||||||||
| Formula | Synonyms | |||||||||||
| 32% Cl | PCB-1232, AROCHLOR 1232, AROCLOR 1232, CHLORODIPHENYL (32 PERCENT CL), PCB 1232, POLYCHLOEINATED BIPHENYL 1232 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 0 | L | 1.44 @ 30°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 3.0 | 150 | 890 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0 | 0 | 0 |
Technical Basis
A review of available sources identified rat oral acute toxicity data (LD50). In addition, analysts evaluated exposure limits for the structurally similar chemical chlorodiphenyl - 42% chlorine (CASRN: 53469-21-9), with comparable toxicity, for TEEL development. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Analysts determined that the use of the IDLH, which reports a combined value for polychlorinated biphenyls (PCBs) with 42% and 54% chlorine, is not advised considering that 54% PCBs are uniquely toxic among PCB congeners. The rat oral LD¬50 was selected as the TEEL-3 basis. The TEEL-2 value was derived according to Table 3.5. The TLV-TWA for chlorodiphenyl – 42% chlorine (CASRN: 53469-21-9) was selected as the TEEL-1 basis (Section 3.4.6).
• PAC-1 = TEEL-1 = TLV-TWA (chlorodiphenyl – 42% chlorine, CASRN: 53469-21-9; 1 mg/m3) x 3
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (4470 mg/kg)
This review generated PAC-3 and PAC-2 values consistent with Rev. 29A, and an inconsistent PAC-1 value. The Rev. 29A and current TEEL-3 and TEEL-2 source, and methodologies are consistent. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 basis is a TLV-TWA for a similar chemical (chlorodiphenyl – 42% chlorine, CASRN: 53469-21-9, Section 3.4.6).
• PAC-1 = TEEL-1 = TLV-TWA (chlorodiphenyl – 42% chlorine, CASRN: 53469-21-9; 1 mg/m3) x 3
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (4470 mg/kg)
This review generated PAC-3 and PAC-2 values consistent with Rev. 29A, and an inconsistent PAC-1 value. The Rev. 29A and current TEEL-3 and TEEL-2 source, and methodologies are consistent. The Rev. 29A TEEL-1 was derived from the TEEL-2, while the current TEEL-1 basis is a TLV-TWA for a similar chemical (chlorodiphenyl – 42% chlorine, CASRN: 53469-21-9, Section 3.4.6).
References
Chemical information, see Table 4-3 and 4-4. Retrieved from: https://www.atsdr.cdc.gov/toxprofiles/tp17-c4.pdf
Rat LD50. Albro PW, Fishbein L. 1974. Intestinal absorption of polychlorinated biphenyls in rats. Bull Environ Contam Toxicol 8:26. Retrieved from: https://semspub.epa.gov/work/01/268620.pdf (see Table 4.1).
IDLH for chlorodiphenyls (42% chlorine and 54% chlorine, CASRN: 53469-21-9 and 11109-69-1 respectively). Retrieved from: https://www.cdc.gov/niosh/idlh/53469219.html
OSHA TWAs for Aroclor 1242 (chlorodiphenyl – 42% chlorine, CASRN: 53469-2): https://www.osha.gov/chemicaldata/392
TLV-TWA for Aroclor 1242 (chlorodiphenyl – 42% chlorine, CASRN: 53469-2): https://www.acgih.org/chlorodiphenyl-42-chlorine/