A review of available sources identified a human (male) TDLo for potassium tellurite, in addition to tellurium exposure limits (CASRN: 13494-80-9, TLV-TWA, IDLH). Data sources were selected according to the hierarchy listed in Table 3.1. The IDLH was evaluated as a TEEL-3 basis; however, it was not selected because it results in a sodium tellurite TEEL-3 greater than tellurium, which is inconsistent with expected relative toxicity. Instead, TDLo toxicity data for potassium tellurite was selected as the TEEL-2 basis and evaluated using factors in Tables 3.2, 3.3, and 3.4. TEEL-3 values were derived according to Table 3.5. The tellurium TLV-TWA was selected as the TEEL-1 basis and a compound adjustment factor was applied (Section 3.2.2).
• TEEL-1 = MW-adjusted TLV-TWA (tellurium, CASRN: 13494-80-9, 0.1 mg/m3) x 3
• TEEL-2 = Human (male) oral TDLo (40 mg/kg/7D; toxicity endpoints reported as: sleep, nausea or vomiting)
• TEEL-3 = TEEL-2 x 6
This review generated TEEL-3 and TEEL-2 values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-1 values, source, and methodology are consistent. The Rev. 29A TEEL-3 and TEEL-2 were derived from the TEEL-1, while the current TEEL-2 is based on human toxicity data, with the TEEL-3 was derived from this value.