PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sodium sulfhydrate; (Sodium hydrosulfide) | 16721-80-5 | 2318 |
18.00
14.01
4.01
11.01
14.02
4.05
7.00
11.00
4.07
|
|||||||||
| Formula | Synonyms | |||||||||||
| HNaS | SODIUM HYDROSULFIDE, SODIUM HYDROSULFIDE (NA(HS)), SODIUM HYDROSULFIDE, SOLID, SODIUM MERCAPTAN, SODIUM MERCAPTIDE, SODIUM SULFHYDRATE, SODIUM SULFIDE (NA(HS)), HIDROSULFURO DE SODIO, SÓLIDO (DOT SPANISH), HYDROGÉNOSULFURE DE SODIUM, SOLIDE (DOT FRENCH), SODIUM HYDROSULFIDE, SODIUM HYDROSULPHIDE, SOLID, SODIUM HYDROSULFIDE, SOLUTION, HIDROSULFIDO DE SODIO, SOLUCIÓN DE (DOT SPANISH), HYDROGÉNOSULFURE DE SODIUM, EN SOLUTION (DOT FRENCH), SODIUM HYDROSULFIDE, WITH NOT LESS THAN 25% WATER OF CRYSTAL, HIDROSULFURO DE SODIO, CON NO MENOS DEL 25% DE AGUA DE CRIST, HYDROGEN SODIUM SULFIDE, HYDROGEN SODIUM SULFIDE (HNAS), | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 56.06 | S | 350 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.32 | 3.5 | 21 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.14 | 1.5 | 9.2 |
Technical Basis
A review of available sources identified rat and mouse LD50 acute toxicity data for intraperitoneal and oral routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The rat oral LD50, that is “the LD50 for the most concentrated commercial form” from an unnamed study on the ECHA Europa website, was selected as the TEEL-3 basis. The TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (105 mg/kg)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat intraperitoneal LD50, however the current TEEL-3 is based on higher priority rat oral LD50 data. The TEEL-2 and TEEL-1 methodologies remain consistent, with the differences in values due to the change of the TEEL-3 basis.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (105 mg/kg)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a rat intraperitoneal LD50, however the current TEEL-3 is based on higher priority rat oral LD50 data. The TEEL-2 and TEEL-1 methodologies remain consistent, with the differences in values due to the change of the TEEL-3 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydrosulfide
Rat oral LD50: https://echa.europa.eu/registration-dossier/-/registered-dossier/15390/7/3/2 (Click "001" from drop-down menu).
Rat intraperitoneal LD50: Biochemical Pharmacology., 38(973), 1989 [PMID:2930598]. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-hydrosulfide.