PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tetrachlorobenzene, 1,2,4,5- | 95-94-3 |
6.00
11.01
4.05
8.00
4.09
4.07
10.00
3.09
3.02
3.10
|
||||||||||
| Formula | Synonyms | |||||||||||
| C6H2Cl4 | 1,2,4,5-TETRACHLOROBENZENE, BENZENE TETRACHLORIDE, RCRA WASTE NUMBER U207, S-TETRACHLOROBENZENE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 215.89 | S | 139.5 | 244.5 | 0.0054 | 25 | 1.858 @ 22°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 4.5 | 50 | 300 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.51 | 5.7 | 34 |
Technical Basis
A review of available sources identified LD50 acute toxicity data for various species (rat, rabbit, mouse) and routes (oral, intraperitoneal). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The data of the most preferred species and route, rat oral LD50, was selected as the TEEL-3 basis. TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (1500 mg/kg)
This review generated TEEL values that are inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 basis and methodology are consistent (rat oral LD50); therefore, differences in the value may be due to the current source being a lower dose. The Rev. 29A TEEL-2 basis was a rat oral TDLo that was not found in the current review; instead, the TEEL-2 was calculated according to Table 3.5. The Rev. 29A and current TEEL-1 values used the same methodology (Table 3.5), with differences due to the change in TEEL-2.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (1500 mg/kg)
This review generated TEEL values that are inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 basis and methodology are consistent (rat oral LD50); therefore, differences in the value may be due to the current source being a lower dose. The Rev. 29A TEEL-2 basis was a rat oral TDLo that was not found in the current review; instead, the TEEL-2 was calculated according to Table 3.5. The Rev. 29A and current TEEL-1 values used the same methodology (Table 3.5), with differences due to the change in TEEL-2.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/1_2_4_5-Tetrachlorobenzene.
Rat oral LD50: Hygiene and Sanitation, 30(1-3)(8), 1965; Found in: National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 7270, 1,2,4,5-Tetrachlorobenzene. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/1_2_4_5-Tetrachlorobenzene.