A review of available sources did not identify exposure limits or acute toxicity data for acrylamide bisacrylamide. This compound is a copolymer of N-N’-methylenebisacrylamide (CASRN: 110-26-9) and acrylamide (CASRN: 79-06-1). Considering this, analysts reviewed GHS health hazard ratings for N-N’-methylenebisacrylamide (H332, inhalation Category 4; H301, H302 oral Category 3 and 4) and acrylamide (H302, oral Category 3); these ratings indicate a mid-level health hazard, approximately equivalent to an HHR=2. Analysts assumed an HHR=2 as the TEEL-3 basis (Section 3.4.5). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = HHR=2
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-1 basis was a TLV-TWA for particles not otherwise specified (Section 3.5.2), from which the TEEL-2 and TEEL-3 were derived (Table 3.5). The current TEEL-3 basis is an assumed HHR=2, from analysis of GHS health hazard statements, from which TEEL-2 and TEEL-1 were derived (Table 3.5).