A review of limited available sources identified the following: LCLo toxicity data for guinea pig, mouse, and rat. Sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were evaluated using the type of exposure, species, and route preferability stated in Sections 3.3.1 and 3.3.2. The concentrations were scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). The rat LCLo was selected as the TEEL-3 basis because it was the most preferred species. As data was insufficient to derive TEEL-2 and TEEL-1, the adjustment factors listed in Table 3.5 were applied.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LCLo (35.3 ppm/6H)
This review generated values that are significantly more conservative than those published in Rev. 29A due to a different basis. In Rev. 29A, the recommendation was a molecular weight adjusted IDLH for fluorides. Upon this review, the chemical is classified as a fluoroacetate, not a fluoride, therefore, the current recommendation is to use available toxicity data as the basis for the TEEL-3 estimate.